Research and prospects on the visual mechanisms and treatment modes of amblyopia  

作　　者：Minbin Yu Yiru Huang Zidong Chen 余敏斌;黄依如;陈子东(State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,China)

机构地区：[1]State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangdong Provincial Clinical Research Center for Ocular Diseases,Guangzhou 510060,China

出　　处：《Eye Science》2024年第4期346-357,共12页眼科学报(英文版)

基　　金：supported by the National Natural Science Foundation of China(82271115,82471115);the Natural Science Foundation Team Project of Guangdong Province Grant(2015A030312016).

摘　　要：Amblyopia is a neurodevelopmental vision disorder resulting from abnormal visual input during the critical period of visual development,such as strabismus,uncorrected anisometropia,high refractive errors,and form deprivation.It is frequently associated with reduced visual acuity and deficits in binocular vision.Traditional occlusion therapy for amblyopia has typically been restricted to infants and young children during the critical period of visual development,as it is believed to be ineffective for older children and adults due to the decreased plasticity of the mature brain.Our research group has concentrated on pivotal scientific issues in amblyopia,including quantitative methods for detecting binocular vision,especially interocular visual suppression,the mechanisms underlying binocular vision impairment in amblyopia,treatment methods and their evaluations for amblyopia,and visual plasticity and its neural mechanisms in amblyopia.This paper summarizes the visual mechanisms and treatment modalities of amblyopia based on our research and both domestic and foreign sources,while also looking forward to the future development of this field in light of existing problems.

关 键 词：AMBLYOPIA binocular vision treatment methods visual plasticity neural mechanisms 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]