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作 者:张玮玮 王健 陶南 刁晓庆 ZHANG Weiwei;WANG Jian;TAO Nan;DIAO Xiaoqing(Department of Endocrine,Donghai Hospital of Traditional Chinese Medicine,Lianyungang,Jiangsu,222300,China;Department of Medical,Donghai Hospital of Traditional Chinese Medicine,Lianyungang,Jiangsu,222300,China;Department of Pharmacy,Donghai Hospital of Traditional Chinese Medicine,Lianyungang,Jiangsu,222300,China)
机构地区:[1]东海县中医院内分泌科,江苏连云港222300 [2]东海县中医院中医科,江苏连云港222300 [3]东海县中医院药剂科,江苏连云港222300
出 处:《当代医学》2024年第22期109-112,共4页Contemporary Medicine
摘 要:目的探讨麦味地黄汤加减治疗老年2型糖尿病(type 2 diabetes mellitus,T2DM)的临床疗效。方法选取2020年5月至2023年5月东海县中医院收治的100例老年T2DM患者作为研究对象,采用随机数字表法分为对照组与观察组,每组50例。对照组采取常规西医治疗,观察组给予麦味地黄汤加减治疗。比较两组治疗前后中医症候积分、血糖水平、不良反应发生率。结果治疗1个月,两组气短乏力、烦渴多饮、潮热盗汗、形体消瘦积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗1个月,两组空腹血糖(fasting blood glucose,FBG)、餐后2 h血糖(postprandial 2 h blood glucose,2 h PBG)水平均低于治疗前,差异有统计学意义(P<0.05),但两组间比较差异无统计学意义。观察组不良反应发生率为4.00%,低于对照组的16.00%,差异有统计学意义(P<0.05)。结论麦味地黄汤加减治疗老年T2DM,能改善患者的中医症候积分,减少不良反应的发生。Objective To analyze the clinical efficacy of the addition and subtraction of Maiwei Dihuang decoction in the treatment of senile type 2 diabetes mellitus(T2DM).Methods 100 senile T2DM admitted to Donghai Hospital of Traditional Chinese Medicine from May 2020 to May 2023 were selected as the research subjects,and they were divided into the control group and the observation groups by random number table method,with 50 cases in each group.The control group received conventional western treatment,and the observation group was treated with the addition and subtraction of Maiwei Dihuang decoction.The Traditional Chinese Medicine(TCM)syndrome score and blood glucose level before and after treatment,and incidence of adverse reactions were compared between the two groups.Results After 1 month of treatment,the scores of shortness of breath and fatigue,polydipsia,hot flushes and night sweats and body wasting of the two groups were lower than those before treatment,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).After 1 month of treatment,the fasting blood glucose(FBG)and postprandial 2 h blood glucose(2 h PBG)levels of the two groups were lower than those before treatment,and the differences were statistically significant(P<0.05),and there was no significant difference between the two groups.The total incidence of adverse reactions in the observation group was 4.00%,which was lower than 16.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion The addition and subtraction of Maiwei Dihuang decoction in the treatment of the senile T2DM,can improve the TCM syndrome score,and reduce the occurrence of adverse reactions.
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