慢性乙型肝炎患者焦虑抑郁现状及发生程度与生命质量的相关性分析  

Analysis of the relationship between anxiety anddepression and quality of life in patients withchronic hepatitis B

作　　者：王宁 艾静 尧敏之 孙文峰[2] 姜丽娟 WANG Ning;AI Jing;YAO Minzhi;SUN Wenfeng;JIANG Lijuan(Quality Control Office,Fuzhou First People's Hospital,Fuzhou,Jiangxi,344000,China;Department of Infection,Fuzhou First People's Hospital,Fuzhou,Jiangxi,344000,China;Department of Psychosomatic Medicine,Fuzhou First People's Hospital,Fuzhou,Jiangxi,344000,China)

机构地区：[1]抚州市第一人民医院质管办,江西抚州344000 [2]抚州市第一人民医院感染科,江西抚州344000 [3]抚州市第一人民医院心身医学科,江西抚州344000

出　　处：《当代医学》2024年第22期135-138,共4页Contemporary Medicine

基　　金：江西省卫生健康委科技计划(202141017)。

摘　　要：目的探讨慢性乙型肝炎(chronic hepatitis B,CHB)患者焦虑抑郁现状及发生程度与生命质量的相关性。方法选取2020年1月至2021年12月抚州市第一人民医院收治的120例CHB患者作为研究对象,均采用焦虑自评量表(self-rating anxiety scale,SAS)、抑郁自评量表(self-rating depression scale,SDS)、世界卫生组织生活简易量表(World Health Organization quality of life brief scale,WHOQOL-BREF)评估焦虑、抑郁及生命质量。统计120例CHB患者的焦虑、抑郁状况及生命质量各领域评分,比较不同焦虑、抑郁状态CHB患者的生命质量评分,探讨CHB患者焦虑、抑郁评分与生命质量评分的相关性。结果120例CHB患者SAS评分平均为(50.63±5.24)分,其中无焦虑67例,轻度焦虑20例,中度焦虑25例,重度焦虑8例;120例CHB患者SDS评分平均为(53.89±5.41)分,其中无抑郁63例,轻度抑郁22例,中度抑郁25例,重度抑郁10例;120例CHB患者WHOQOL-BREF评分中,心理领域评分平均为(75.63±6.28)分、生理领域评分平均为(76.82±6.31)分、环境领域评分平均为(79.41±6.55)分、社会领域评分平均为(78.49±6.45)分。合并焦虑患者心理、生理、环境、社会领域评分低于无焦虑患者,差异有统计学意义(P<0.05);合并抑郁患者心理、生理、环境、社会领域评分低于无抑郁患者,差异有统计学意义(P<0.05);SAS评分、SDS评分与心理、生理、环境及社会领域评分呈负相关(r<0,P<0.05)。结论CHB患者合并焦虑、抑郁风险较高,且焦虑、抑郁与生命质量呈负相关,临床还需开展积极有效措施,以消除患者焦虑、抑郁状态,改善生命质量。Objective To explore the relationship between anxiety and depression in patients with chronic hepatitis B(CHB)and the quality of life.Methods A total of 120 CHB patients admitted to Fuzhou First People's Hospital from January 2020 to December 2021 were selected as research subjects.Self-rating anxiety scale(SAS),self-rating depression scale(SDS),the World Health Organization Quality of Life Brief Scale(WHOQOL-BREF)were used to assess anxiety,depression and quality of life.The anxiety and depression status,as well as scores in various areas of quality of life of 120 CHB patients were analyzed,the quality of life scores of CHB patients with different anxiety and depression were compared,and the correlation between anxiety and depression scores and quality of life scores of CHB patients was discussed.Results The average SAS score of 120 patients with CHB was(50.63±5.24)scores,including 67 patients with no anxiety,20 patients with mild anxiety,25 patients with moderate anxiety,and 8 patients with severe anxiety;the average SDS score of 120 patients with CHB was(53.89±5.41)scores,including 63 cases of no depression,22 cases of mild depression,25 cases of moderate depression and 10 cases of severe depression;The average WHOQOL-BREF score of 120 patients with CHB was(75.63±6.28)scores in psychological field,(76.82±6.31)scores in physiological field,(79.41±6.55)scores in environmental field and(78.49±6.45)scores in social field;the scores of psychological,physiological,environmental and social fields in the patients with anxiety were lower than those in the patients without anxiety,and the differences were statistically significant(P<0.05),the scores of psychological,physiological,environmental and social fields in patients with anxiety were lower than those in patients without anxiety,and the differences were statistically significant(P<0.05);the scores of psychological,physiological,environmental and social fields in patients with depression were lower than those in patients without depression,and the differences

关 键 词：慢性乙型肝炎 焦虑 抑郁 生命质量 相关性 

分 类 号：R47[医药卫生—护理学]