低频脉冲电磁场联合运动干预对老年骨质疏松患者骨密度及生存质量的影响  

Effects of low frequency pulsed electromagnetic field combined with exercise intervention on bone mineral density and quality of life in elderly patients with osteoporosis

作　　者：刘丽杰 吴丹丹 初佳欣 崔倩[2] LIU Li-Jie;WU Dan-Dan;CHU Jia-Xin(Jinqiu Hospital of Liaoning Province,Shenyang 110067,Liaoning,China)

机构地区：[1]辽宁省金秋医院,辽宁沈阳110067 [2]中国医科大学盛京医院

出　　处：《吉林医学》2025年第1期27-31,共5页Jilin Medical Journal

基　　金：辽宁省自然基金指导计划[项目编号:2019-ZD-0425]。

摘　　要：目的:分析低频脉冲电磁场联合运动干预对老年骨质疏松患者骨密度及生存质量的影响。方法:选取2021年3月~2023年3月在辽宁省金秋医院接受治疗的老年骨质疏松患者65例,随机数字法将其分为两组。两组均给予基础抗骨质疏松治疗,运动组(n=32)患者给予运动干预,仪器组(n=33)则在其基础上加用低频脉冲电磁场治疗。对比两组患者不同部位的骨密度、生存质量、实验室指标及不良反应。结果:干预前,两组三个不同部位的骨密度比较差异无统计学意义(P>0.05);干预后,两组股骨颈(Neck)、三角(Ward)、腰椎L 2~L 4的骨密度均高于治疗前,且仪器组腰椎L 2~L 4的骨密度高于运动组,差异有统计学意义(P<0.05),但两组Neck、Ward骨密度比较差异无统计学意义(P>0.05);干预后,两组患者健康状况调查简表(SF-36)中8个维度评分高于治疗前,且仪器组高于运动组,差异有统计学意义(P<0.05);干预后,两组骨钙素(OC)、Ⅰ型胶原氨基端前肽(PINP)、Ⅰ型胶原羧基末端肽交联β特殊序列(β-CTX)均低于干预前,且仪器组低于运动组,差异有统计学意义(P<0.05);两组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论:针对老年骨质疏松患者,给予低频脉冲电磁场联合运动干预可有效提高患者骨密度,改善骨代谢指标,提高其生存质量,且安全性良好。Objective To analyze the effects of low frequency pulsed electromagnetic field combined with exercise intervention on bone mineral density and quality of life in elderly patients with osteoporosis.Method A total of 65 elderly patients with osteoporosis who received treatment in Jinqiu Hospital of Liaoning Province from March 2021 to March 2023 were selected and divided into two groups by random number method.Both groups were given basic anti-osteoporosis therapy,exercise group(n=32)was given exercise intervention,and instrument group(n=33)was given low-frequency pulsed electromagnetic field therapy.Bone mineral density,quality of life,laboratory indexes and adverse reactions in different parts of the two groups were compared.Results Before intervention,there was no significant difference in the BMD of the two groups(P>0.05).After intervention,the BMD of femoral Neck,triangular Ward and lumbar L 2~L 4 in both groups was higher than before treatment,and the BMD of lumbar L 2~L 4 in the instrument group was higher than that in the exercise group(P<0.05),but there was no significant difference in BMD of Neck and Ward between the two groups(P>0.05).After intervention,the scores of 8 dimensions in the SF-36 were higher in the two groups than before treatment,and the instrument group was higher than the exercise group(P<0.05);After intervention,OC,PINP andβ-CTX in 2 groups were lower than before intervention,and the instrument group was lower than the exercise group(P<0.05);There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion For elderly patients with osteoporosis,low-frequency pulsed electromagnetic field combined with exercise intervention can effectively improve bone mineral density,improve bone metabolism indexes,and improve their quality of life,with good safety.

关 键 词：低频脉冲电磁场 运动干预 老年 骨质疏松 骨代谢指标 

分 类 号：R681.1[医药卫生—骨科学]