乙肝疫苗接种预防控制婴幼儿乙型肝炎感染的效果分析  

Analysis of the Effect of Hepatitis B Vaccination in the Prevention and Control of Infant Hepatitis B Infection

作　　者：袁玉敏 YUAN Yumin(Center for Disease Control and Prevention,Xinyu,Jiangxi 336600,China)

机构地区：[1]江西省分宜县疾病预防控制中心,江西新余336600

出　　处：《中国医药指南》2025年第2期118-120,共3页Guide of China Medicine

摘　　要：目的探讨乙肝疫苗接种预防控制婴幼儿乙型肝炎感染的效果。方法选取分宜县2022年10月至2023年10月完成全程接种乙肝疫苗的60名婴幼儿作为研究对象,记录在接种疫苗1年和两年后的乙型肝炎抗体浓度,并分析在接种1年和两年后的乙型肝炎表面抗体(HBsAb)反应情况。结果接种疫苗1年后,乙型肝炎抗体的平均滴度为(118.33±3.30)mU/ml,高于接种两年后的(93.23±1.25)mU/ml(P<0.05)。接种1年后的HBsAb阳性率为96.67%,高于接种两年后的78.33%(P<0.05)。结论乙型肝炎疫苗接种可预防幼儿乙型肝炎感染。Objective To explore the effectiveness of hepatitis B vaccination in preventing and controlling hepatitis B infection in infants and young children.Methods A total of 60 infants and young children who completed the full course of hepatitis B vaccination from October 2022 to October 2023 in Fenyi County were selected as the study subjects.The concentration of hepatitis B antibodies was recorded one and two years after vaccination,and the response of hepatitis B surface antibody(HBsAb)one and two years after vaccination was analyzed.Results One year after vaccination,the average titer of hepatitis B antibodies was(118.33±3.30)mU/ml,which was higher than that after two years(93.23±1.25)mU/ml(P<0.05).The positive rate of HBsAb one year after vaccination was 96.67%,which was higher than 78.33%after two years(P<0.05).Conclusions Hepatitis B vaccination can prevent hepatitis B infection in young children.

关 键 词：乙型肝炎病毒 乙肝疫苗 婴幼儿 乙型肝炎预防 

分 类 号：R512.62[医药卫生—内科学] R186[医药卫生—临床医学]