红光和蓝光联合域发生发液及5%米诺地尔酊治疗Ⅰ型女性雄激素脱发的疗效研究  

Efficacy of red and blue lights combined with Yufa Shengfa solution and 5%minoxidil solution in treating type Ⅰ female androgenetic alopecia

作　　者：戴晨蕾 刘军 孙晓明 杨镜徽 马江 王雨璇 陈菊萍 DAI Chenlei;LIU Jun;SUN Xiaoming;YANG Jinghui;MA Jiang;WANG Yuxuan;CHEN Juping(Department of Dermatology and Venereal Diseases,the Affiliated Hospital of Yangzhou University,Yangzhou,Jiangsu,225000)

机构地区：[1]扬州大学附属医院皮肤与性病科,江苏扬州225000

出　　处：《实用临床医药杂志》2024年第24期10-14,共5页Journal of Clinical Medicine in Practice

摘　　要：目的探讨红光和蓝光联合域发生发液及5%米诺地尔酊治疗I型女性雄激素脱发的疗效。方法将160例Ludwig分型I型女性雄激素脱发患者随机分为4组,即A组(域发生发液联合5%米诺地尔酊)、B组(红光和蓝光照射联合域发生发液)、C组(红光和蓝光照射联合5%米诺地尔酊)、D组(红光和蓝光照射联合域发生发液和5%米诺地尔酊),每组40例。所有患者口服复方甘草酸苷片、善存复合维生素片,治疗周期为3个月。比较治疗前后毛发直径、毛发密度、多根毛发毛囊单位个数的差异。结果4组患者毛发密度、毛发直径、多根毛发毛囊单位个数均较治疗前改善,且D组在毛发密度、毛发直径、多根毛发毛囊单位个数方面的改善效果最佳,差异均有统计学意义(P<0.001)。所有患者在治疗期间无严重不良事件或副作用。结论红光和蓝光联合域发生发液及5%米诺地尔酊治疗Ⅰ型女性雄激素脱发效果显著,是一种有效的非手术治疗方式。Objective To investigate the efficacy of red and blue lights combined with Yufa Shengfa solution and 5%minoxidil solution in treating Ludwig type Ⅰ female androgenetic alopecia.Methods A total of 160 patients with Ludwig type Ⅰ female androgenetic alopecia were randomly divided into group A(Yufa Shengfa solution combined with 5%minoxidil solution),group B(red and blue lights therapy combined with Yufa Shengfa solution),group C(red and blue lights therapy combined with 5%minoxidil solution)and group D(red and blue lights therapy combined with Yufa Shengfa solution and 5%minoxidil solution),with 40 cases in each group.All the patients orally took compound glycyrrhizin tablets and Centrum multivitamins,and the therapeutic period was 3 months.Differences in hair diameter,hair density,and the number of hair follicles with multiple hairs were compared before and after treatment.Results The hair density,hair diameter,and the number of hair follicles with multiple hairs improved significantly in 4 groups compared with those before treatment,and group D showed the best improvement in these parameters,with significant between-group differences(P<0.001).There were no serious adverse events or side effects during treatment in all the patients.Conclusion Red and blue lights therapy combined with Yufa Shengfa solution and 5%minoxidil solution is an effective non-surgical treatment for Ludwig type I female androgenetic alopecia.

关 键 词：女性雄激素脱发 红光 蓝光 米诺地尔酊 域发生发液 

分 类 号：R751.05[医药卫生—皮肤病学与性病学] R758.7[医药卫生—临床医学] R753.3