坏死松解性游走性红斑1例  

Necrolytic Migratory Erythema:A Case Report

作　　者：张牧秋 汪盛[1] ZHANG Muqiu;WANG Sheng(Department of Dermatology,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院皮肤性病科,四川成都610041

出　　处：《中国皮肤性病学杂志》2025年第1期105-108,共4页The Chinese Journal of Dermatovenereology

摘　　要：患者男,44岁,全身反复红斑、糜烂伴瘙痒3年。皮肤科情况:头面部、躯干、四肢弥漫性红斑,边缘呈地图状改变,部分红斑上出现水疱、糜烂,糜烂面覆盖褐色厚层痂壳。腹部增强CT提示“胰体尾部占位伴不均匀强化”,行“腹腔镜下胰体尾切除术”,术后病理显示为胰高血糖素瘤。诊断:坏死松解性游走性红斑,胰高血糖素瘤综合征。术后3 d起患者皮损迅速消退,20 d内临床痊愈,遗留少量色素沉着,随访6个月无复发。A 44-year-old male presented with recurrent erythema,erosion and pruritus throughout the entire body for 3 years.Dermatological examination demonstrated diffuse erythema on the face,head,trunk and extremities,with irregular borders.Vesicles and erosions with thick brown crusts appeared on the basis of a few erythema.Enhanced abdominal CT scan revealed a mass in the body and tail of the pancreas with uneven enhancement.Laparoscopic distal pancreatectomy was performed,and glucagonoma was finally confirmed by postoperative pathologic examination.The diagnosis of necrolytic migratory erythema and glucagonoma syndrome was established.The lesions were dramatically relieved within 3 days after surgery,and the patient achieved clinical cure in 20 days,with a few pigmentation left.There have been no clinical evidence of recurrence during the 6-month follow-up period.

关 键 词：坏死松解性游走性红斑 胰高血糖素瘤 

分 类 号：R758.61[医药卫生—皮肤病学与性病学]