西洋参中皂苷类成分表征和炮制导致成分转化的研究进展  

Research Progress on Characterization of Saponin Components in American Ginseng and Component Transformation Caused by Processing

作　　者：刘忠英[1] 李瑜 刘舒[2] 后宗 汪戎锦 LIU Zhongying;LI Yu;LIU Shu;HOU Zong;WANG Rongjin(College of Pharmacy,Jilin University,Changchun 130021,China;Key Laboratory of Traditional Chinese Medicine Chemistry and Mass Spectrometry Jilin Province,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China)

机构地区：[1]吉林大学药学院,长春130021 [2]中国科学院长春应用化学研究所,吉林省中药化学与质谱重点实验室,长春130022

出　　处：《吉林大学学报(理学版)》2025年第1期229-240,共12页Journal of Jilin University:Science Edition

基　　金：吉林省与中国科学院科技合作高技术产业化专项基金(批准号:2024SYHZ0044);吉林省科技厅青年成长科技项目(批准号:20240602085RC);吉林省教育厅优秀青年项目(批准号:JJKH20241348KJ);国家自然科学基金青年基金(批准号:82304693).

摘　　要：西洋参富含多种药理活性物质,具有保护心血管系统、改善神经系统疾病和降血糖等多种药理作用,目前对西洋参中皂苷类成分的结构表征及炮制转化研究取得了显著进展.总结概括西洋参中皂苷类活性成分的分类和分布、现代主流分析技术以及炮制加工对皂苷类成分的转化机制,为西洋参皂苷类成分的深入挖掘和创新炮制技术等提供有效的技术支撑和指导方法,从而扩大其在医疗和保健等方面的应用.American ginseng was rich in various pharmacological active substances,which had various pharmacological effects such as protecting the cardiovascular system,improving neurological diseases,and lowering blood sugar,significant progress had been made in the structural characterization and processing transformation research of saponin components in American ginseng.We summarized the classification and distribution of saponin active components in American ginseng,modern mainstream analytical techniques,and the transformation mechanism of saponin components by processing,providing effective technical support and methodological guidance for the in-depth exploration of saponin components in American ginseng and innovative processing techniques,thereby expanding its applications in medical treatment,health care and other aspects.

关 键 词：西洋参 皂苷 串联质谱 炮制加工 

分 类 号：R917[医药卫生—药物分析学]