梅毒感染对孕产妇不良情绪及新生儿结局的影响研究  

Research on the influence of syphilis infection on maternal negative emotions and neonatal outcomes

作　　者：周燕 周珊娜 方萌琛 ZHOU Yan;ZHOU Shanna;FANG Mengchen(Department of Obstetrics and Gynecology,Zhoushan Women and Children's Hospital,Zhoushan 316000,Zhejiang,China)

机构地区：[1]舟山妇女儿童医院妇科,浙江舟山316000

出　　处：《中国性科学》2025年第1期143-146,共4页Chinese Journal of Human Sexuality

基　　金：2020年浙江省医药卫生科技项目(2020KY194)。

摘　　要：目的探究梅毒感染对孕产妇不良情绪及新生儿结局的影响。方法以2021年1月至2023年6月舟山妇女儿童医院分娩的11050例孕产妇为研究对象,统计孕产妇梅毒感染发生率。对比梅毒感染与正常孕产妇孕晚期不良情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)评分]及新生儿结局,且分析不同特征梅毒感染孕产妇临床指标差异。结果孕产妇梅毒感染率为1.00%(100/11050),梅毒母婴传播率为7.00%。梅毒感染孕产妇孕晚期SAS、SDS评分均显著高于正常孕产妇(P<0.05),梅毒感染孕产妇不良新生儿结局发生率(13.00%)高于正常孕产妇(2.01%)(P<0.05)。初检梅毒血清滴度试验(RPR)滴度≥1∶16、非规范治疗/未治疗的梅毒感染孕产妇SAS、SDS评分及不良新生儿结局发生率均显著高于滴度<1∶16、规范治疗者(P<0.05);不同梅毒确诊时间孕产妇SAS、SDS评分对比差异显著(P<0.05),而不良新生儿结局发生率对比差异无统计学意义(P>0.05)。结论梅毒感染易让孕产妇产生焦虑、抑郁情绪,增加不良新生儿结局,加强梅毒筛查、及时发现和治疗梅毒的同时积极进行心理疏导有利于改善新生儿结局。Objective To explore the influence of syphilis infection on maternal negative emotions and neonatal outcomes.Methods A total of 11,050 pregnant women who gave birth in Zhoushan Women and Children's Hospital from January 2021 to June 2023 were selected as the research objects to count the incidence of syphilis infection in pregnant women.The negative emotions[self-rating anxiety scale(SAS)score,self-rating depression scale(SDS)score]and neonatal outcomes were compared between syphilis infection and normal pregnant women in late pregnancy stage,and the indexes of syphilis infection women with different characteristics were analyzed.Results The rate of syphilis infection in pregnant women was 1.00%(100/11,050),and the mother-to-child transmission rate was 7.00%.The SAS score and SDS score of syphilis infected pregnant women in the late pregnancy stage were significantly higher than those of normal pregnant women(P<0.05),and the incidence of adverse neonatal outcomes(13.00%)was significantly higher than that of normal pregnant women(2.01%)(P<0.05).The SAS score,SDS score and incidence of adverse neonatal outcomes in pregnant women with syphilis infection with rapid plasma reagin(RPR)titer≥1∶16 and non-standard treatment/untreated were significantly higher than those with titer<1∶16 and standard treatment(P<0.05).There were significant differences in SAS scores and SDS scores among pregnant women at different time of syphilis diagnosis(P<0.05),but there was no statistically significant difference in the incidence of adverse neonatal outcomes(P>0.05).Conclusions Syphilis infection is likely to cause emotions of anxiety and depression in pregnant women and increase adverse neonatal outcomes.Strengthening syphilis screening,timely detection and treatment of syphilis and meanwhile positive psychological counseling are conducive to improving neonatal outcomes.

关 键 词：梅毒感染 孕产妇 不良情绪 新生儿结局 

分 类 号：R759[医药卫生—皮肤病学与性病学]