超高效液相色谱-串联质谱法同时测定水中两类含氟新污染物  

Simultaneous determination of two types of emerging fluorinated pollutants in water by ultra high performance liquid chromatography-tandem mass spectrometry

作　　者：周画天 黄帝 刘晓雨 王献礼 饶钦雄[2] 刘成斌 宋卫国[2] ZHOU Huatian;HUANG Di;LIU Xiaoyu;WANG Xianli;RAO Qinxiong;LIU Chengbin;SONG Weiguo(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Institute for Agri-food Standards and Testing Technology,Shanghai Academy of Agricultural Sciences,Shanghai 201403,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海200093 [2]上海市农业科学院农产品质量标准与检测技术研究所,上海201403

出　　处：《分析试验室》2024年第12期1655-1661,共7页Chinese Journal of Analysis Laboratory

基　　金：上海市优秀技术带头人(23XD1432900);卓越团队(沪农科卓[2022]010)项目资助;国家自然科学基金(22006113)资助。

摘　　要：建立了一种同时测定水中17种全氟化合物(PFCs)和13种氟喹诺酮类抗生素(FQs)的超高效液相色谱-串联质谱(UPLC-MS/MS)分析方法。17种PFCs和13种FQs在0.1~100μg/L范围内线性良好,相关系数(R)均大于0.996,方法检测限(LOD)和定量限(LOQ)分别为0.01~0.30 ng/L和0.04~1.00 ng/L。在不同加标水平下,目标化合物的回收率在64.1%~111%之间,相对标准偏差(RSD)为0.9%~13%。将该方法用于检测工业废水中的2类含氟化合物,共检出9种化合物,其中全氟辛酸(PFOA)检出量最大,为118 ng/L。该方法可用于水样中2类含氟污染物的分析检测。A method based on ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)was developed for simultaneous determination of 17 perfluorinated compounds(PFCs)and 13 fluoroquinolones(FQs)in water.The linear range of the 17 PFCs and 13 FQs was 0.1-100μg/L,with correlation coefficients(R)above 0.996.The method limits of detection(LODs)and limits of quantification(LOQs)were 0.01-0.30 ng/L and 0.04-1.00 ng/L,respectively.The recoveries of the target compounds with different spiked levels were in the range of 64.1%-111%,and the relative standard deviations(RSDs)from 0.9%to 13%.This method was applied to detect two novel fluorinated compounds in the industrial wastewater from pesticide plants.Totally,9 compounds were detected.Perfluorooctanoic acid(PFOA)was detected at the highest level of 118 ng/L.This method is capable of employing for the detection of two novel fluorine-containing pollutants in water samples.

关 键 词：固相萃取 超高效液相色谱-串联质谱 水 全氟化合物 氟喹诺酮类抗生素 

分 类 号：O657.63[理学—分析化学] X832[理学—化学]