出 处:《中国现代药物应用》2024年第24期98-101,共4页Chinese Journal of Modern Drug Application
摘 要:目的 观察小儿龋齿手术中瑞芬太尼复合丙泊酚静脉麻醉与七氟烷吸入麻醉的应用效果。方法 60 例行龋齿手术治疗的患儿 , 采用随机数字表法分为对照组和观察组 , 每组 30 例。对照组采用瑞芬太尼复合丙泊酚静脉麻醉 , 观察组采用七氟烷吸入麻醉。对比两组患儿不同时刻[麻醉前 (T_(0))、手术开始时 (T_(1))]的心率、平均动脉压 , 麻醉起效时间、术后呼吸恢复时间、咽喉反射恢复时间、苏醒时间、喉罩拔除时间 , 不良反应发生率。结果 T_(0)时 , 两组患儿心率、平均动脉压对比差异无统计学意义(P>0.05)。T_(1)时 , 对照组患儿心率、平均动脉压均较本组 T_(0)时明显降低 , 差异具有统计学意义 (P<0.05);观察组患儿心率、平均动脉压与本组 T_(0)时对比无明显变化 , 差异无统计学意义 (P>0.05)。T_(1)时 , 观察组患儿心率 (95.68±2.02) 次 /min、平均动脉压 (69.79±1.65)mm Hg(1 mm Hg=0.133 kPa) 高于对照组的(82.76±1.95) 次 /min、(61.15±1.42)mm Hg, 差异具有统计学意义 (P<0.05)。观察组患儿麻醉起效时间、术后呼吸恢复时间、咽喉反射恢复时间、苏醒时间、喉罩拔除时间均略短于对照组 , 但差异无统计学意义 (P>0.05)。观察组患儿不良反应发生率 3.33% 低于对照组的 20.00%, 差异具有统计学意义 (P<0.05)。结论 七氟烷吸入麻醉和瑞芬太尼复合丙泊酚静脉麻醉应用于小儿龋齿手术中均有一定的效果 , 其中 ,七氟烷吸入麻醉对患儿生命体征的影响更小 , 不良反应更少 , 值得临床优先应用和推广。Objective To observe the practical effect of sevoflurane inhalation anesthesia and remifentanil-propofol intravenous anesthesia for dental caries surgery in children.Methods 60 children who underwent surgical treatment for dental caries were divided into a control group and an observation group using a random numerical table,with 30 cases in each group.The control group was given remifentanil-propofol intravenous anesthesia,and the observation group was given sevoflurane inhalation anesthesia.Comparison was made on the heart rate and mean arterial pressure at different time points[before anesthesia(T_(0))and at the beginning of surgery(T_(1))],the onset time of anesthesia,postoperative respiratory recovery time,pharyngeal reflex recovery time,wake-up time,laryngeal mask removal time,and the incidence of adverse reactions between the two groups.Results At T_(0),there was no significant difference in heart rate and mean arterial pressure between the two groups(P>0.05).At T_(1),the heart rate and mean arterial pressure in the control group were significantly lower than those at T_(0) in this group,and the difference was statistically significant(P<0.05).In the observation group,there were no significant changes in heart rate and mean arterial pressure at T_(1) compared with those at T_(0) in this group,and the difference was not statistically significant(P>0.05).At T_(1),the observation group had heart rate of(95.68±2.02)beats/min and mean arterial pressure of(69.79±1.65)mm Hg(1 mm Hg=0.133 kPa),which were higher than(82.76±1.95)beats/min and(61.15±1.42)mm Hg in the control group,and the difference was statistically significant(P<0.05).The onset time of anesthesia,postoperative respiratory recovery time,pharyngeal reflex recovery time,wake-up time,and laryngeal mask removal time in the observation group were slightly shorter than those in the control group,but the difference was not statistically significant(P>0.05).The incidence rate of adverse reactions in the observation group was 3.33%,which was lower than 2
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