无痛胃肠镜检查中利多卡因静脉给药的麻醉辅助效果及研究进展  

Study on the Auxiliary Anesthetic Effect of Intravenous Administration of Lidocaine in Painless Gastroenteroscopy

作　　者：陈洁[1] 汪小海[1,2] 王尔华[1] CHEN Jie;WANG Xiaohai;WANG Erhua(Department of Anesthesiology,Nanjing Drum Tower Hospital Affiliated to Medical College of NanjingUniversity,Nanjing 210008,China;Department of Anesthesiology,Taikang Xianlin Drum Tower Hospital Affiliated to Medical College of Nanjing University,Nanjing 210046,China)

机构地区：[1]南京大学医学院附属鼓楼医院麻醉科,南京210008 [2]南京大学医学院附属泰康仙林鼓楼医院麻醉科,南京210046

出　　处：《药学与临床研究》2024年第6期535-539,共5页Pharmaceutical and Clinical Research

摘　　要：无痛胃肠镜检查在临床应用广泛,患者在镇静睡眠中接受检查,疼痛与不适感得到显著减轻。丙泊酚是无痛胃镜检查中常用的镇静全麻药,但可能引发循环和呼吸抑制。利多卡因静脉给药(IVL)作为麻醉辅助用药,可减少手术应激反应,降低麻醉中镇痛与镇静药物用量,提升手术安全性并利于术后恢复,目前亦作为无痛胃肠镜的辅助用药。本文对IVL用于无痛胃肠镜麻醉的效果及最新研究进行综述。Painless gastrointestinal and colonal endoscopy are commonly used in clinical practice as a method of receiving examination under sedation and sleep state,during which patients experience significantly reduced pain and discomfort.Propofol,a general anesthetic,is commonly used in painless gastroscopy due to its ability to significantly reduce pain and discomfort during the examination.However,propofol anesthesia may result in cardiovascular and respiratory suppression.Lidocaine administered intravenously(IVL)as an adjuvant anesthesia can effectively reduce surgical stress responses,reduce the amount of anesthesia and analgesic drugs during the surgery,thereby improving surgical safety and contributing to better patient recovery.This usage has now been extended to general anesthesia and painless gastrointestinal endoscopy,where IVL has been used as an adjuvant anesthetic.This article summarizes the effects of IVL as an adjuvant anesthetic for painless gastrointestinal endoscopy and its latest research.

关 键 词：无痛胃肠镜检查 丙泊酚 利多卡因 镇静剂 辅助作用 

分 类 号：R614[医药卫生—麻醉学]