心脏MR评估射血分数保留型心力衰竭病人心肌纤维化的研究进展  

Research progress on cardiac MR evaluation of myocardial fibrosis in heart failure with preserved ejection fraction

作　　者：陈思玟 马运婷 赵晓莹 赵新湘(审校)[1] CHEN Siwen;MA Yunting;ZHAO Xiaoying;ZHAO Xinxiang(Department of Radiology,The Second Affiliated Hospital of Kunming Medical University,Kunming 650000,China;Department of Radiology,Panzhihua Central Hospital)

机构地区：[1]昆明医科大学第二附属医院放射科,昆明650000 [2]攀枝花市中心医院放射科

出　　处：《国际医学放射学杂志》2025年第1期74-80,共7页International Journal of Medical Radiology

基　　金：国家自然科学基金项目(82160332);云南省科技厅科技计划项目(202201AY070001-097);云南省科技平台与人才项目(202305AF150033);北京医学奖励基金会(YXJL-2022-0665-0214)。

摘　　要：射血分数保留型心力衰竭(HFpEF)是一种异质性大且病因复杂的疾病,其中心肌纤维化是驱动HFpEF病人心功能障碍的主要病理生理机制。心脏MR(CMR)的延迟钆增强(LGE)、T1 mapping、细胞外容积(ECV)及CMR特征追踪(CMR-FT)等多种技术已用于评估HFpEF病人心肌纤维化,可评价心肌纤维化的分布、程度,能够对HFpEF病人进行风险分层和预后评估。综述CMR技术在HFpEF病人心肌纤维化中的研究进展,同时展望人工智能在优化CMR检查中的应用潜力。Heart failure with preserved ejection fraction(HFpEF)is a condition characterized by high heterogeneity and complex etiologies.Among its various underlying mechanisms,myocardial fibrosis is a key pathophysiological factor contributing to cardiac dysfunction in HFpEF patients.This article reviews the progress in applying various cardiac magnetic resonance(CMR)techniques,including delayed gadolinium enhancement(LGE),T1 mapping,extracellular volume(ECV),and CMR feature tracking(CMR-FT),to assess myocardial fibrosis in HFpEF.It highlights the role of these techniques in evaluating the distribution and severity of myocardial fibrosis,as well as their utility in risk stratification and prognostic assessment.Additionally,the article explores the future potential of artificial intelligence in enhancing CMR-based evaluations.

关 键 词：心力衰竭 射血分数 舒张性心力衰竭 心肌纤维化 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]