宫颈小细胞神经内分泌癌治疗的研究进展  

Research progress in the treatment of small cell neuroendocrine cervical carcinoma

作　　者：向雪松 丁景新 XIANG Xue-song;DING Jing-xin(Department of Gynecological Oncology,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200090,China)

机构地区：[1]复旦大学附属妇产科医院妇科肿瘤科,上海200090

出　　处：《复旦学报(医学版)》2025年第1期128-132,共5页Fudan University Journal of Medical Sciences

基　　金：上海市自然科学基金(21ZR1410400)。

摘　　要：宫颈小细胞神经内分泌癌(small cell neuroendocrine cervical carcinoma,SCNECC)是一种罕见的妇科恶性肿瘤,早期容易出现侵袭转移,预后比宫颈鳞癌和腺癌差。目前对其临床管理尚处于探索阶段,近年来,随着国内外对SCNECC的关注越来越多,改善其预后的探索也取得一些成果。本文将SCNECC综合治疗的研究进展作一综述,对当前手术、放化疗、靶向与免疫药物等治疗策略中的一些关键问题进行探讨和展望。Small cell neuroendocrine cervical carcinoma(SCNECC)is a rare gynecological malignancy characterized by early invasion and metastasis,resulting in a poorer prognosis compared to cervical squamous cell carcinoma and adenocarcinoma.The clinical management of SCNECC remains in the exploratory phase.Recently,as this uncommon tumor has garnered increasing attention both domestically and internationally,some progress has been made in improving its prognosis.This article summarizes the advancements in combined modality therapy for SCNECC,discussing and providing insights into key issues related to current treatment strategies of surgery,radiotherapy and chemotherapy,as well as targeted and immunotherapies.

关 键 词：宫颈癌 小细胞神经内分泌癌(SCNECC) 综合疗法 

分 类 号：R711.74[医药卫生—妇产科学]