血压异常波动的高血压患者冠状动脉病变及相关因素分析  

Analysis of coronary artery disease and related factors in hypertensive patients with abnormal blood pressure fluctuation

作　　者：丁绍祥 陆威 蒋旋志 许月皎 杨芳圆 DING Shaoxiang;LU Wei;JIANG Xuanzhi;XU Yuejiao;YANG Fangyuan(Department of Geriatrics,Wuxi No.2 Geriatric Hospital,Jiangsu,Wuxi 214174,China)

机构地区：[1]江苏省无锡市第二老年病医院老年科,江苏无锡214174

出　　处：《中国医药科学》2024年第24期116-119,174,共5页China Medicine And Pharmacy

基　　金：江苏省无锡市科协重点申报课题(KX-21-C237);江苏省老年健康科研面上课题(LKM2023033)。

摘　　要：目的 探讨血压异常波动的高血压患者冠状动脉(简称“冠脉”)血管病变及相关影响因素。方法 选取2020年4月至2024年3月无锡市第二老年病医院老年科行冠脉造影且符合高血压病3级患者276例,根据入院后血压监测数据,分为血压异常波动组72例和血压正常波动组204例,按冠脉造影结果、性别、年龄、是否合并糖尿病、缺血性脑卒中、高脂血症、颈部血管斑块、冠脉钙化进行统计分析。结果 血压异常波动组与正常波动组间糖尿病、缺血性脑卒中、高脂血症、颈部血管斑块发生率比较,差异无统计学意义(P> 0.05);冠脉钙化发生率组间差异有统计学意义(P <0.05);冠脉重度狭窄发生率组间差异有统计学意义(P <0.05)。logistic回归分析结果显示,冠脉重度狭窄和冠脉钙化是高血压患者血压异常波动的危险因素(P <0.05)。结论 血压异常波动的高血压患者冠脉重度狭窄风险增加,冠脉钙化多见。Objective To explore coronary artery disease and related influencing factors in hypertensive patients with abnormal blood pressure fluctuations.Methods From April 2020 to March 2024,276 patients with grade 3hypertension who underwent coronary angiography in the Department of Geriatrics,Wuxi No.2 Geriatric Hospital were selected.According to the blood pressure monitoring data after admission,they were divided into 72 patients with abnormal blood pressure fluctuations and 204 patients with normal blood pressure fluctuations.Statistical analysis was carried out according to the results of coronary angiography,gender,age,whether there was diabetes,ischemic stroke,hyperlipidemia,cervical vascular plaque,and coronary calcification.Results There was no significant difference in the incidence of diabetes,ischemic stroke,hyperlipidemia and cervical vascular plaque between the abnormal blood pressure fluctuation group and the normal fluctuation group(P > 0.05).There was a statistically significant difference in the incidence of coronary artery calcification between the two groups(P < 0.05).There was a statistically significant difference in the incidence of severe coronary stenosis between the two groups(P < 0.05).The results of logistic regression analysis showed that severe coronary stenosis and coronary calcification were risk factors for abnormal blood pressure fluctuations in hypertensive patients(P < 0.05).Conclusion Hypertensive patients with abnormal blood pressure fluctuations have an increased risk of severe coronary stenosis and are more prone to coronary calcification.

关 键 词：高血压 血压波动 冠状动脉造影术 糖尿病 高脂血症 缺血性脑卒中 

分 类 号：R541.6[医药卫生—心血管疾病]