武汉市孕中期妇女抑郁发生情况及影响因素研究  

Prevalence and Influencing Factors of Depression Among Pregnant Women in Midterm in Wuhan City:A Cross-Sectional Study

作　　者：邹丽 谭乐 马玉巧 崔宁宁 杨雪锋[2] Zou Li;Tan Le;Ma Yuqiao(Hanyang Maternal and Child Health Hospital,Wuhan 430050,China;Department of Nutrition and Food Hygiene,Hubei Key Laboratory of Food Nutrition and Safety,MOE Key Laboratory of Environment and Health,School of Public Health,Tongji Medical College,Huazhong Universityof Science and Technology,Wuhan 430030,China)

机构地区：[1]武汉市汉阳区妇幼保健院,武汉430050 [2]华中科技大学同济医学院公共卫生学院营养与食品卫生学系,食品营养与安全湖北省重点实验室,武汉430030

出　　处：《华中科技大学学报(医学版)》2024年第6期825-832,共8页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：2023年武汉市医学科学研究项目(No.WX23B03);国家自然科学基金面上项目(No.82173511)。

摘　　要：目的了解武汉市孕中期妇女抑郁发生情况并分析抑郁的影响因素。方法采用横断面研究设计,选取2023年7月1日至2024年3月1日于武汉市汉阳区妇幼保健院参加孕期保健服务的2134名孕中期妇女作为研究对象。使用爱丁堡产后抑郁量表(EPDS)评估孕期抑郁状况,通过问卷调查收集一般人口学信息、妊娠状况、睡眠时间、膳食摄入、规律锻炼等行为和生活方式。利用膳食多样性评分评估孕妇膳食质量,采用二元Logistic回归分析孕中期抑郁的影响因素。结果纳入研究的2134例孕妇中,孕中期抑郁检出率为10.59%(226例)。在调整年龄、家庭月收入、文化程度、产次和异常孕产史等混杂因素后,二元Logistic回归分析显示文化程度较高(OR=0.69,95%CI:0.51~0.92)、膳食多样性评分较高(OR=0.46,95%CI:0.30~0.71)、规律锻炼(OR=0.61,95%CI:0.39~0.97)的孕妇抑郁检出率较低。夜间睡眠时间<7 h(OR=2.08,95%CI:1.36~3.17)、人工辅助生殖(OR=1.54,95%CI:1.03~2.30)、孕前吸烟(OR=2.21,95%CI:1.25~3.90)、孕前饮酒(OR=2.25,95%CI:1.34~3.77)、孕期中重度呕吐(OR=1.49,95%CI:1.12~1.98)、孕期膳食口味油腻(OR=2.19,95%CI:1.45~3.29)的孕妇抑郁检出率较高。结论应加强对孕期抑郁的关注,加大健康宣教力度。鼓励孕妇保持健康饮食,不吸烟饮酒,保证充足的睡眠,规律锻炼,培养健康行为习惯,以减少孕期抑郁的发生。Objective To investigate the prevalence of depression among the second-trimester pregnant women in Wuhan and explore the related factors of depression.Methods A cross-sectional study was performed including 2134 pregnant women in the second-trimester who attended pregnancy health care services in Hanyang Maternal and Child Healthcare Hospital in Wuhan from July 1st,2023 to March 1st,2024.The Edinburgh Postnatal Depression Scale(EPDS)was used to assess depression during pregnancy.Behaviors and lifestyles including general demographic information,pregnancy status,sleep time,dietary intake,and regular exercise were collected through questionnaires.Dietary diversity score was used to evaluate the recent dietary status of pregnant women,and binary logistic regression was used to analyze the influencing factors of depression in the second trimester.Results Among 2134 pregnant women,the detection rate of depression in the second trimester was 10.59%(226 cases).After adjusting for confounding factors such as age,family monthly income,education level,parity and abnormal pregnancy history,binary logistic regression analysis showed that pregnant women with higher education level(OR=0.69,95%CI:0.51~0.92),higher dietary diversity score(OR=0.46,95%CI:0.30~0.71),and regular exercise(OR=0.61,95%CI:0.39~0.97)had lower detection rate of depression.Pregnant women with artificial assisted reproduction(OR=1.54,95%CI:1.03~2.30),nighttime sleep duration<7 h(OR=2.08,95%CI:1.36~3.17),smoking history before pregnancy(OR=2.21,95%CI:1.25~3.90),alcohol intake history before pregnancy(OR=2.25,95%CI:1.34~3.77),moderate to severe vomiting during pregnancy(OR=1.49,95%CI:1.12~1.98),and greasy diet during pregnancy(OR=2.19,95%CI:1.45~3.29)were at higher risk of depression.Conclusion Attention should be paid to depression during pregnancy,and health education should be strengthened.Pregnant women should be encouraged to maintain a healthy diet,do not smoke and drink,ensure adequate sleep,exercise regularly,and cultivate healthy behavior habits,so a

关 键 词：孕中期 抑郁 膳食多样性评分 影响因素 

分 类 号：R714.25[医药卫生—妇产科学]