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作 者:侯亚林 曹丽丽 段秀红 王娇 樊晶晶 王韶军 HOU Yalin;CAO Lili;DUAN Xiuhong;WANG Jiao;FAN Jingjing;WANG Shaojun(Zhangjiakou Traditional Chinese Medicine Hospital of Hebei Province,Zhangjiakou 075000,China)
出 处:《上海针灸杂志》2024年第12期1363-1367,共5页Shanghai Journal of Acupuncture and Moxibustion
基 金:张家口市重点研发计划项目(2221148D)。
摘 要:目的观察药线点灸联合散寒活血祛白方治疗白癜风的临床疗效及其对患者皮损面积和生活质量的影响。方法将100例白癜风患者根据随机数字表法分为观察组和对照组,每组50例。对照组内服散寒活血祛白方联合白斑处外用散寒活血祛白酊治疗,观察组在对照组治疗基础上于白斑部位行药线点灸治疗。比较两组临床疗效和不良反应发生情况,观察两组治疗前后白癜风面积评分指数(vitiligo area scoring index,VASI)、皮肤病生活质量指数(dermatologylifequalityindex,DLQI)和中医证候积分的变化。结果两组治疗后VASI、DLQI和中医证候积分均降低(P<0.05),观察组VASI、DLQI及中医证候积分均低于对照组(P<0.05)。观察组总有效率显著高于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论在内服散寒活血祛白方联合白斑处外用散寒活血祛白酊基础上,药线点灸治疗白癜风可提高临床疗效,可更好地缩小皮损面积,进一步提高患者的生活质量。Objective To observe the clinical efficacy of medicinal thread moxibustion plus San Han Huo Xue Qu Bai formula in treating vitiligo and the effects on the patient’s skin lesion area and quality of life.Method One hundred vitiligo patients were divided into an observation group and a control group using the random number table method,each group consisting of 50 cases.Both groups applied San Han Huo Xue Qu Bai tincture to the affected areas.In addition,the control group orally took San Han Huo Xue Qu Bai formula,based on which the observation group received medicinal thread moxibustion at the affected regions.The clinical efficacy and adverse reactions were compared between the two groups.The vitiligo area scoring index(VASI),dermatology life quality index(DLQI),and symptom and sign score of traditional Chinese medicine(TCM)were observed before and after the treatment.Result After the treatment,the VASI,DLQI,and TCM symptom and sign score dropped in both groups(P<0.05)and were lower in the observation group than in the control group(P<0.05).The total effective rate was significantly higher in the observation group than in the control group(P<0.05).There was no significant difference in comparing the adverse reaction rate between the two groups(P>0.05).Conclusion Compared to the sole use of San Han Huo Xue Qu Bai formula,it can produce better clinical efficacy when used together with medicinal thread moxibustion in treating vitiligo,as this combined method can more significantly reduce skin lesion area and enhance the patient’s quality of life.
分 类 号:R246.7[医药卫生—针灸推拿学]
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