2型糖尿病的内脏型肥胖患者中骨量变化的机制研究及相关治疗  

Mechanism of Bone Mass Change in Patients with Visceral Obesity in Type 2 Diabetes Mellitus and Related Treatments

作　　者：郑雨端 阿不来提·艾则孜[2] ZHENG Yuduan;Abulaiti Aizezi(Graduate School of Xinjiang Medical University,Urumqi 830017,China;不详)

机构地区：[1]新疆医科大学研究生学院,新疆乌鲁木齐830017 [2]新疆维吾尔自治区人民医院全科医疗科,新疆乌鲁木齐830000

出　　处：《中国医学创新》2025年第3期175-180,共6页Medical Innovation of China

摘　　要：内脏型肥胖及2型糖尿病(type 2 diabetes mellitus,T2DM)的患病率随着我国生活和经济的发展、老龄化趋势的严峻在不断上升,对人们的健康及生活质量产生了严重的影响。两者均可对骨骼健康造成严重破坏,从而引发骨质疏松症(osteoporosis,OP)。除了人们熟知的遗传因素、生活方式、饮食习惯、性激素、年龄等可以影响骨骼健康以外,本文将从脂肪因子、肌因子、骨因子、肝因子和炎症细胞因子等几方面来阐述内脏型肥胖对T2DM患者骨量变化的影响,并对内脏型肥胖的诊断及T2DM肥胖患者的相关治疗进行综述。The prevalence of visceral obesity and diabetes mellitus type 2(T2DM)is increasing with the development of China's life and economy and the severity of the aging trend,which has a serious impact on people's health and quality of life.Both can wreak havoc on bone health,leading to osteoporosis(OP).In addition to the well-known genetic factors,lifestyle,dietary habits,sex hormones,age,etc.,which can affect bone health,this article will elaborate on the effects of visceral obesity on bone mass changes in patients with T2DM from the aspects of fat factor,muscle factor,bone factor,liver factor and inflammatory cytokine,and review the diagnosis of visceral obesity and the related treatment of patients with T2DM obesity.

关 键 词：内脏肥胖 2型糖尿病 机制 骨密度 

分 类 号：R587.2[医药卫生—内分泌] R580[医药卫生—内科学]