超高效液相色谱-串联质谱法测定复杂水质中25种全氟/多氟化合物  

Determination of 25 per-and polyfluoroalkyl substances in complex water by ultra high performance liquid chromatography-tandem mass spectrometry

在线阅读下载全文

作  者:吴萍 王炜 刘惠敏 段秀锋 曲腊腊 尤本胜[1] WU Ping;WANG Wei;LIU Huimin;DUAN Xiufeng;QU lala;YOU Bensheng(Jiangsu Provincial Academy of Environmental Science,State Environmental Protection Key Laboratory of Aquatic Ecosystem Health in the Middle and Lower Reaches of Yangtze River,Nanjing 210000,China)

机构地区:[1]江苏省环境科学研究院,国家环境保护长江中下游水生态健康重点实验室,南京210000

出  处:《化学分析计量》2025年第1期12-20,共9页Chemical Analysis And Meterage

基  金:江苏省生态环境保护专项资金省本级项目(AEHZK2023002)。

摘  要:建立超高效液相色谱-串联质谱测定复杂水质中25种全氟/多氟化合物(PFASs)含量的分析方法。样品经直接过滤、乙腈提取或固相萃取,用Agilent Eclipse Plus C_(18)色谱柱分离,以含0.01%甲酸的甲醇溶液和水作为流动相,梯度洗脱,在电喷雾负离子模式下,采用多反应监测模式检测,用内标法定量。25种PFASs的质量浓度在0.5~100μg/L范围内与色谱峰面积线性关系良好,相关系数均大于0.999,3种样品处理方法的检出限分别为0.06~0.20、0.002~0.006μg/L和0.1~0.2 ng/L。样品加标平均回收率为69.9%~115%,测定结果的相对标准偏差为2.9%~19.6%(n=6)。该方法简单快捷、重现性好、灵敏度较高,适用于氟化工园区污水、地表水和地下水中25种PFASs的测定。A method of determination of 25 per-and polyfluoroalkyl substance(PFASs)in complex water by ultra high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)was established.The samples were subjected to directly filter,acetonitrile extraction or solid-phase extraction,and then separated by Agilent Eclipse Plus C_(18)with 0.01% formic acid methanol solution and water as the mobile phase for gradient elutionisation and determined by UPLC-MS/MS,in which negative electrospray ionization as well as multiple reaction monitoring mode was used in the detection,and quantified by internal standard method.The mass concentration of 25 PFASs had a good linear relationship with the chromatographic peak area in the range of 0.5-100μg/L,the correlation coefficients were all more than 0.999,and the detection limit of direct injection,acetonitrile extraction and solid phase extraction were 0.06-0.20,0.002-0.006μg/L and 0.1-0.2 ng/L,respectively.The average spiked recoveries of the samples were 69.9%-115%,and the relative standard deviations of the determination results were 2.9%-19.6%(n=6).The method is simple,rapid,reproducible,and sensitive,and it can meet the determination of 25 PFASs in fluorochemical industrial park sewage,surface water and groundwater.

关 键 词:全氟/多氟化合物 超高效液相色谱-串联质谱法 直接进样 乙腈提取 固相萃取 

分 类 号:O657.7[理学—分析化学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象