儿童幽门螺杆菌感染性消化性溃疡相关危险因素分析  

Analysis of Risk Factors for Helicobacter Pylori Positive Peptic Ulcer in Children

作　　者：程如金 尹闪闪 CHENG Rujin;YIN Shanshan(Pediatric Intensive Care Unit,Nanyang Central Hospital,Nanyang,Henan 473000,China)

机构地区：[1]南阳市中心医院儿童重症监护病区,河南南阳473000

出　　处：《中国烧伤创疡杂志》2025年第1期75-78,共4页The Chinese Journal of Burns Wounds & Surface Ulcers

摘　　要：目的探讨分析儿童幽门螺杆菌感染性消化性溃疡的相关危险因素。方法选取2021年2月至2023年2月南阳市中心医院收治的73例消化性溃疡患儿作为研究对象,收集患儿性别、年龄、家族史、饮食结构、生活习惯、有无非甾体类抗炎药应用史、有无心理障碍、幽门螺杆菌感染情况等相关资料,根据是否感染幽门螺杆菌将其分为感染组和非感染组,分析消化性溃疡患儿存在幽门螺杆菌感染的相关危险因素。结果73例消化性溃疡患儿中51例(69.86%)感染幽门螺杆菌,设为感染组;22例(30.14%)未感染幽门螺杆菌,设为非感染组。多因素Logistic回归分析结果显示,性别为男性、年龄≥6岁、有家族史、经常吃外卖、偏爱酸辣、偏爱冷食、住校/小餐桌、有非甾体类抗炎药应用史、有心理障碍是消化性溃疡患儿存在幽门螺杆菌感染的独立危险因素(95%CI为1.155~1.771、1.027~2.539、1.660~224.735、1.028~11.010、1.114~2.499、1.015~5.162、2.864~145.463、1.289~15.651、1.024~1.569,P=0.001、0.038、0.018、0.045、0.012、0.046、0.003、0.018、0.029)。结论性别、年龄、有无家族史、是否经常吃外卖、是否偏爱酸辣、是否偏爱冷食、是否住校/小餐桌、有无非甾体类抗炎药应用史、有无心理障碍是儿童幽门螺杆菌感染性消化性溃疡的独立影响因素。Objective To analyze the risk factors for helicobacter pylori positive peptic ulcer in children.Methods 73 children with peptic ulcers,admitted to Nanyang Central Hospital between February 2021 and February2023,were selected as research subjects.Data were collected including sex,age,family history,dietary structure,living habits,history of application of non-steroidal anti-inflammatory drug,psychological disorders,and helicobacter pylori infection.Patients were divided into the infection group and the non-infection group based on the occurrence of helicobacter pylori infection.The risk factors of helicobacter pylori infection in children with peptic ulcer were analyzed.Results 51(69.86%)of the 73 children patients with peptic ulcer developed helicobacter pylori infection,which were set as the infection group,while the other 22(30.14%)children patients without developing helicobacter pylori infection were set as the non-infection group.The results of multivariate Logistic regression analysis showed that male children with age≥6 years,family history,frequent takeaways diet,hot and sour taste preference,cold food preference,boarding in at the school or dining at small dining tables,history of application of non-steroidal anti-inflammatoiy drug,and psychological disorders were the independent risk factors for helicobacter pylori infection in children with peptic ulcers(95%CI:1.155-1.771,1.027-2.539,1.660-224.735,1.028-11.010,1.114-2.499,1.015-5.162,2.864-145.463,1.289-15.651,1.024-1.569,P=0.001,0.038,0.018,0.045,0.012,0.046,0.003,0.018 and 0.029).Conclusion Sex,age,family history,frequent takeaways diet,hot and sour taste preference,cold food preference,boarding in at the school or dining at small dining tables,history of application of non-steroidal anti-inflammatory drug,and psychological disorders were independent risk factors for helicobacter pylori infection in children with peptic ulcers.

关 键 词：儿童 消化性溃疡 幽门螺杆菌感染 危险因素 LOGISTIC回归分析 

分 类 号：R725.7[医药卫生—儿科]