反刍动物初乳microRNA组成和功能研究进展  

Research Progress on Composition and Function of Colostral MicroRNA in Ruminants

作　　者：孙同玉 马涛[1] SUN Tongyu;MA Tao(Key Laboratory of Feed Biotechnology,Ministry of Agriculture and Rural Affairs,Institute of Feed Research,Chinese Academy of Agricultural Sciences,Beijing 100081,China)

机构地区：[1]中国农业科学院饲料研究所,农业农村部饲料生物技术重点实验室,北京100081

出　　处：《畜牧兽医学报》2025年第1期74-81,共8页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：财政部和农业农村部:国家现代农业产业技术体系专项(CARS-38)。

摘　　要：反刍动物初乳中含有丰富的生物活性成分,其中microRNA是一类非编码RNA,可在转录后水平调节基因的表达,对于母体乳腺以及幼龄反刍动物肠道发育具有重要的调控作用。近年来,反刍动物初乳microRNA组成和功能的研究开始受到关注,本文综述了反刍动物初乳中microRNA的来源、组成及其影响因素、功能,以及目前研究的局限性和未来的研究方向,为生产高品质初乳,提高母仔一体化培育水平提供理论支撑。The colostrum of ruminants encompasses abundant bioactive components,of which microRNAs are kind of non-coding RNAs that can regulate gene expression at the post-transcriptional level and play important roles in regulating development of the mother’s mammary gland and gastrointestinal tract of young ruminants.In recent years,studies on the profile and function of microRNAs derived from ruminant colostrum have attracted attention.In this review,the source,composition,influencing factors,and function of microRNA in ruminant colostrum as well as the limitations of current studies and future research directions were summarized,with an aim to provide theoretical support for the production of high-quality colostrum and improve integrated mother-neonate cultivation level.

关 键 词：反刍动物 初乳 MICRORNA 胞外囊泡 

分 类 号：S823.91[农业科学—畜牧学]