《外科随机对照试验的统计与方法指南》解读:基于JAMA Surgery的报道(一)  

Interpretation of“Guidelines for statistics and methods in surgical randomized controlled trials”:Based on reports from JAMA Surgery(Part One)

作　　者：胥月晴 孔雕 彭伟[1] 李川[1] 文天夫[1] XU Yueqing;KONG Diao;PENG Wei;LI Chuan;WEN Tianfu(Division of Liver Surgery,Department of General Surgery,West China Hospital,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院普外科,肝脏外科病房,成都610041

出　　处：《中国普外基础与临床杂志》2025年第1期28-34,共7页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省自然科学基金(项目编号:2024NSFSC0637)。

摘　　要：为了应对外科临床研究中长期存在的挑战,现对2022-2023年期间在JAMA Surgery发表的关于随机对照试验(randomized controlled trials,RCT)方法指导的系列文章进行了深入解读。本部分内容重点介绍了RCT的设计、选择、伦理考量、质量控制、预算、经费支持等方面的内容,旨在增强研究者,特别是外科医生对RCT的全面理解,从而为临床外科医生开展更高质量和更具科学性的RCT研究提供方法学指导。To address the persistent challenges in surgical clinical research,we provide a comprehensive analysis of the series of articles on randomized controlled trials(RCTs)methodology guidance published in JAMA Surgery from 2022 to 2023.This section contents focus on critical aspects of RCTs,including trial design,selection criteria,ethical considerations,quality control,budgeting,and funding support.The objective is to enhance the understanding of RCTs among researchers,particularly surgeons,thereby guiding them in conducting high-quality and scientifically robust RCTs.

关 键 词：随机对照试验 设计 伦理 质量控制 经费支持 

分 类 号：R73[医药卫生—肿瘤]