儿童百白破疫苗接种不良反应发生情况分析  

Analysis of Adverse Reactions in Children Receiving Diphtheria Pertussis Tetanus Vaccine

作　　者：孙琳琳 邴启爱 江军红 刘杰静 Sun Linlin;Bing Qi’ai;Jiang Junhong;Liu Jiejing(Xiazhuang Subdistrict Community Healthcare Center of Chengyang District,Qingdao,Shandong,2661092,China)

机构地区：[1]青岛市城阳区夏庄街道社区卫生服务中心,山东青岛266109 [2]青岛市城阳区疾病预防控制中心,山东青岛266109 [3]青岛市城阳区城阳街道社区卫生服务中心,山东青岛266109

出　　处：《中国初级卫生保健》2025年第1期77-78,87,共3页Chinese Primary Health Care

摘　　要：目的:探讨儿童吸附无细胞百白破联合疫苗(以下简称百白破疫苗)接种不良反应发生情况,为相关疾病的预防工作提供依据。方法:选取2021年1月—2023年6月在青岛市城阳区城阳街道预防接种门诊接受百白破疫苗预防接种的7 118名儿童,其中接种基础针的儿童4 834人,接种加强针的儿童2 284人。分析接种基础针、加强针儿童不良反应发生情况,不良反应的影响因素及干预治疗措施。结果:7 118名儿童中共有73名儿童发生不良反应,主要包括红肿、疼痛、硬结、发热、哭闹。接种加强针的儿童不良反应发生率为1.93%,高于接种基础针的儿童(0.60%),差异有统计学意义(χ^(2)=29.890,P<0.05)。结论:儿童接种百白破疫苗多出现不良反应,应认真分析不良反应发生情况,切实做好接种预防和护理,保证疫苗接种的安全性和时效性,为儿童身心健康保驾护航。OBJECTIVE To explore the occurrence of adverse reactions of diphtheria pertussis tetanus(DPT)vaccination in children and related prevention and nursing.METHODS From January 2021 to June 2023,children who received diphtheria,tetanus and acellular pertussis combined vaccine vaccination in Chengyang Street vaccination clinic in Chengyang District were selected as the research objects.A total of 7118 doses were administered,including 4834 doses of basic needles and 2284 doses of booster needles.To analyze the occurrence of adverse reactions in children vaccinated with basic needle and booster needle,the influencing factors of adverse reactions and the intervention measures.RESULTS A total of 73 children of 7118 children had adverse reactions,including swelling,pain,induration,fever and crying.The probability of adverse reactions in children vaccinated with booster needles was 1.93%,which was higher than that of basic needles(0.60%).The difference between the two groups was statistically significant(χ^(2)=29.890,P<0.05).CONCLUSION Children inoculated with adsorbed cell-free diphtheria-pertussis-tetanus vaccine often have adverse reactions.The occurrence of adverse reactions should be carefully analyzed,and vaccination prevention and nursing should be done well to ensure the safety and timeliness of vaccination and protect children’s physical and mental health.

关 键 词：疫苗接种 不良反应 百白破 护理 

分 类 号：R186[医药卫生—流行病学]