胰岛素过量死亡的法医学研究进展  

Advances in forensic research on fatal insulin overdose

作　　者：卞存浩 王琪 何鑫 李剑波[1] Bian Cunhao;Wang Qi;He Xin;Li Jianbo(Department of Forensic Medicine,Faculty of Basic Medical Sciences,Chongqing Engineering Research Center for Criminal Investigation Technology,Chongqing Medical University)

机构地区：[1]重庆医科大学基础医学院法医学系/重庆市刑事侦查技术工程研究中心,重庆400016

出　　处：《重庆医科大学学报》2024年第12期1479-1482,共4页Journal of Chongqing Medical University

基　　金：国家重点研发计划资助项目(编号:2022YFC2600804)。

摘　　要：胰岛素作为体内维持葡萄糖稳态的重要激素,在糖尿病治疗中至关重要。近年来,随着外源性胰岛素广泛使用,胰岛素过量意外、自杀、他杀案件不断增加。由于胰岛素过量尸体的注射部位难发现、病理征象不明显、死后血中胰岛素降解快及死后的血生化波动大等特点,导致胰岛素过量死亡的法医学诊断极其困难。因此,本文综述了胰岛素过量的原因、致死机制、病理变化、毒化分析和鉴定要点,为胰岛素过量死亡的法医学鉴定提供帮助。Insulin,as an important hormone that maintains glucose homeostasis in the body,is crucial in the treatment of diabetes.In recent years,with the widespread use of exogenous insulin,there has been a constant increase in insulin overdose accidents,suicides,and homicides.The forensic diagnosis of fatal insulin overdose is extremely difficult due to the difficulties in identifying the injection site,the lack of obvious pathological signs,the rapid degradation of insulin in postmortem blood,and the large fluctuation of blood biochemistry after death.Therefore,this article reviews the causes,lethal mechanisms,pathological changes,toxicological analysis,and identification points of insulin overdose,so as to provide help for the forensic identification of fatal insulin overdose.

关 键 词：法医病理学 胰岛素过量 毒理学 综述 

分 类 号：R473.72[医药卫生—护理学]