OSA危险人群与耳鸣患病的相关性研究  

Study on the Relevance of People at Risk of Obstructive Sleep Apnea and Tinnitus

作　　者：刘佳丽 杨键 袁炜 谭韵 李洪涛 LIU Jiali;YANG Jian;YUAN Wei;TAN Yun;LI Hongtao(Department of Otolaryngology,the Third Affiliated Hospital of Chongqing Medical University,Chongqing 401120,China)

机构地区：[1]重庆医科大学附属第三医院耳鼻咽喉科,重庆401120

出　　处：《听力学及言语疾病杂志》2025年第1期55-58,共4页Journal of Audiology and Speech Pathology

摘　　要：目的 探讨阻塞性睡眠呼吸暂停(obstructive sleep apnea, OSA)与耳鸣患病的相关性。方法 选取2005-2008年和2015-2018年美国国家健康和营养调查(NHANES)中年龄≥20岁且参与了耳鸣和睡眠问卷调查者的相关数据,使用STOP-Bang问卷确定OSA危险人群,并通过Logistic回归模型分析OSA危险人群与耳鸣患病的相关性。结果 在最终纳入的5 183例参与者中,非耳鸣组约占83.3%(4 320/5 183),耳鸣组约占16.7%(863/5 183)。耳鸣组STOP-Bang分数(3.71±1.51)比非耳鸣组(2.81±1.62)高(P<0.001);OSA低危组、中危组、高危组耳鸣的患病率分别为8.1%(175/1 973)、20.5%(435/1 689)、27.8%(253/658)(均为P<0.001)。多因素Logistic回归模型显示OSA中危组、高危组较低危组的耳鸣患病风险逐步增加,OR值及95%可信区间分别为2.348(1.920~2.871)、3.136(2.488~3.953)(均为P<0.001)。结论 OSA危险人群是耳鸣患病的独立危险因素,OSA风险程度越高者,耳鸣的患病率及患病风险越高。Objective To investigate the relation between obstructive sleep apnea(OSA)and tinnitus.Methods The data of subjects aged 20 years or above who participated in tinnitus and sleep questionnaire survey from the 2005-2008 and 2015-2018 National Health and Nutrition Surveys(NHANES)had been used,the people at risk of OSA were selected via the STOP-Bang questionnaire,and the association between the people at risk of OSA and tinnitus was determined by a Logistic regression model.Results Among the 5183 participants,83.3%(4320/5183)and 16.7%(863/5183)were classified into the non-tinnitus and tinnitus group,respectively.The tinnitus group had higher STOP-Bang scores(3.71±1.51)than those of the group without tinnitus(2.81±1.62)(P<0.001).The observed prevalence rates of tinnitus in the low-risk,middle-risk and high-risk group were 8.1%(175/1973),20.5%(435/1689),27.8%(253/658),respectively.The multivariate Logistic regression model showed that patients with middle-risk and high-risk of OSA had an increased risk of tinnitus compared with low-risk group,with the OR values and confidence intervals of 2.348(1.920~2.871)and 3.136(2.488~3.953),respectively(P<0.001).Conclusion People at risk of OSA are independently risk factors of tinnitus.Higher risk of OSA is associated with higher prevalence and higher risk of tinnitus.

关 键 词：耳鸣 阻塞性睡眠呼吸暂停 危险因素 

分 类 号：R764.45[医药卫生—耳鼻咽喉科]