虫草素抗肿瘤新型给药系统研究进展  

Research Progress on New Anti-tumor Drug Delivery System of Cordycepin

作　　者：池杰明 CHI Jieming(Department of Pharmacy,Fuzhou First General Hospital,Fuzhou,Fujian,350000,China)

机构地区：[1]福州市第一总医院药学部,福建福州350000

出　　处：《中外医疗》2024年第35期195-198,共4页China & Foreign Medical Treatment

摘　　要：虫草素在临床研究领域中为重点研究对象,其有多种药理活性,但虫草素在体内的稳定性较差、可以被腺苷脱氨酶快速代谢,所以临床应用进展不够理想,因此需要通过对载体给药系统进行深入研究,突破虫草素临床应用局限性,以改善虫草素临床应用缺陷。本文从虫草素抗肿瘤作用机制、虫草素抗肿瘤应用领域、虫草素抗肿瘤给药系统进行综述,旨在于通过给药系统进一步发挥虫草素抗肿瘤优势,以达到确切的临床用药干预效果。Cordycepin shows a variety of pharmacological activities and is the focus of attention in the field of clinical research.Due to the lack of stability in vivo and rapid metabolism by adenosine deaminase,the progress of clinical application is not ideal.Therefore,it is necessary to break through the limitations of clinical application of cordycepin by means of in-depth study of carrier drug delivery system,so as to improve the clinical application defects of cordycepin.

关 键 词：虫草素 抗肿瘤 机制 给药系统 

分 类 号：R285.5[医药卫生—中药学]