静脉滴注泼尼松辅助微创旋切术与传统治疗方案治疗非哺乳期乳腺炎的效果比较  

Comparison of the Efficacy of Intravenous Prednisone-Assisted Minimally Invasive Rotary Cutting Surgery and Traditional Treatment Regimen for Non-Puerperal Mastitis

作　　者：宋倩 李兰亚 朱莉 SONG Qian;LI Lanya;ZHU Li(Department of Laboratory,Shuyang County Hospital of Traditional Chinese Medicine,Shuyang,Jiangsu 223600,China;Department of Breast Surgery,Shuyang County Hospital of Traditional Chinese Medicine,Shuyang,Jiangsu 223600,China)

机构地区：[1]江苏省沭阳县中医院检验科,江苏沭阳223600 [2]江苏省沭阳县中医院甲乳外科,江苏沭阳223600

出　　处：《临床误诊误治》2025年第3期83-88,共6页Clinical Misdiagnosis & Mistherapy

基　　金：国家重点研发计划“主动健康和老龄化科技应对”重点专项(2021YFC2009300)。

摘　　要：目的比较静脉滴注泼尼松辅助微创旋切术与传统方案治疗非哺乳期乳腺炎(NPM)的临床效果。方法选取2018年4月至2020年3月收治的163例NPM患者,随机分为观察组82例和对照组51例。观察组采用静脉滴注泼尼松辅助微创旋切术治疗,对照组采用传统治疗方案进行治疗。比较2组治疗总有效率、满意度、红细胞沉降率及C反应蛋白、血清免疫球蛋白水平,观察2组复发及不良反应发生情况。结果观察组总有效率[93.90%(77/82)]高于对照组[82.72%(67/81)],差异有统计学意义(P<0.05)。治疗后,2组红细胞沉降率、C反应蛋白及血清免疫球蛋白均较治疗前降低,且观察组低于对照组(P<0.05,P<0.01);2组复发率和不良反应发生率比较差异无统计学意义(P>0.05)。结论静脉滴注泼尼松辅助微创旋切术治疗NPM效果较好,且安全性较高。Objective To compare the clinical effect of intravenous Prednisone-assisted minimally invasive rotary cutting surgery and traditional treatment regimen for non-puerperal mastitis(NPM).Methods A total of 163 patients with NPM admitted from April 2018 to March 2020 were randomly divided into the observation group(n=82)and the control group(n=51).The observation group was treated with intravenous Prednisone-assisted minimally invasive rotary cutting surgery,while the control group was treated with traditional treatment regimen.The total effective rate,satisfaction rate,erythrocyte sedimentation rate(ESR),C reactive protein(CRP)and serum immunoglobulin levels were compared between the two groups,and the recurrence and adverse reactions were observed.Results The total effective rate of the observation group[93.90%(77/82)]was higher than that of the control group[82.72%(67/81)],and the difference was significant(P<0.05).After treatment,ESR,CRP and serum immunoglobulin in the two groups were lower than those before treatment,which were lower in the observation group than in the control group(P<0.05,P<0.01).There was no significant difference in the recurrence rate and the incidence of adverse reactions between the two groups(P>0.05).Conclusion Intravenous Prednisone-assisted minimally invasive rotary cutting surgery is effective and safe in the treatment of NPM.

关 键 词：非哺乳期乳腺炎 微创旋切术 泼尼松 红细胞沉降率 C反应蛋白 免疫球蛋白 复发 

分 类 号：R655.8[医药卫生—外科学]