北京市某区不同出生队列6~35月龄儿童流脑疫苗基础免疫接种情况及影响因素分析  

Analysis of basic immunization status and influencing factors of cerebrospinal meningitis vaccine among children aged 6-35 months in different birth cohorts in a certain district of Beijing

作　　者：唐莹[1] 王凤双[1] 李春龙[1] 彭枭然 TANG Ying;WANG Fengshuang;LI Chunlong;PENG Xiaoran(Immunization Planning Department,Beijing Shunyi District Center for Disease Control and Prevention,Beijing 101300,China)

机构地区：[1]北京市顺义区疾病预防控制中心免疫规划科,北京101300

出　　处：《职业与健康》2024年第22期3073-3077,共5页Occupation and Health

摘　　要：目的了解北京市某区不同出生队列6~35月龄儿童流脑疫苗基础免疫接种情况,探讨适龄儿童流脑疫苗基础免疫全程接种情况影响因素。方法使用“北京市免疫规划信息管理系统”查询并导出2017年7月1日—2022年2月28日出生儿童流脑疫苗基础免疫接种资料,描述A群脑膜炎球菌多糖疫苗(group A meningococcal polysaccharide vaccine,MPV-A)和A群C群脑膜炎球菌多糖结合疫苗(group A and C meningococcal polysaccharideconjugate vaccine,MPCV-AC)接种率变化趋势,整理疑似预防接种异常反应(adverse events following immunization,AEFI)和规范化门诊资料,对适龄儿童流脑疫苗基础免疫全程接种情况影响因素进行多因素分析。结果北京市某区儿童流脑疫苗基础免疫覆盖率为98.58%,其中MPCV-AC基础免疫覆盖率呈逐年上升趋势(χ^(2)_(趋势)=487.08,P<0.01);北京市户籍、城区地区居住儿童、女孩、MPCV-AC流脑疫苗接种、AA级门诊接种、所在门诊每周门诊日频率>3次、所在门诊登记台数>3台、所在门诊接种台数>3台的儿童流脑疫苗基础免疫全程完成率较高[OR(95%CI)=0.37(0.35~0.39)、0.81(0.74~0.88)、1.07(1.01~1.12)、5.45(1.34~22.23)、1.12(1.00~1.25)、1.22(1.12~1.34)、1.02(1.01~1.29)、1.18(1.06~1.31)]。结论北京市某区6~35月龄儿童流脑疫苗基础免疫覆盖率较高,可将预防接种宣传重点放在流动儿童和农村地区,加强服务人口数较小门诊的预防接种工作,提高全区流脑疫苗基础免疫接种水平。Objective To investigate the basic immunization status of children aged 6-35 months in different birth cohorts with cerebrospinal meningitis vaccine in a district of Beijing,and to explore the influencing factors of the full course immunization status of children with epidemic cerebrospinal meningitis vaccine.Methods The"Beijing Immunization Planning Information Management System"was used to query and export the basic immunization data of children born from July 1,2017 to February28,2022.The trend of change in the vaccination rates of group A meningococcal polysaccharide vaccine(MPV-A)and group A and C meningococcal polysaccharide conjugate vaccine(MPCV-AC)were described,and adverse events following immunization(AEFI)and standardized outpatient data were sorted out.Multivariate analysis was conducted on the influencing factors of the entire process vaccination of meningococcal vaccine in eligible children.Results The basic immunization coverage rate of children's meningitis vaccine in a district of Beijing was 98.58%,of which the basic immune coverage rate of MPCV-AC was increasing year by year(χ^(2)_(Trend)=487.08,P<0.01).Children with registered residence in Beijing,children living in urban areas,girls,MPCV-AC meningococcal vaccination,AA outpatient vaccination,the frequency of weekly outpatient days in their outpatient clinics>3,the number of registered outpatient clinics>3,and the number of vaccinations in their outpatient clinics>3 had a high completion rate of basic immunization of meningococcal vaccines[OR(95%CI)=0.37(0.35-0.39)、0.81(0.74-0.88)、1.07(1.01-1.12)、5.45(1.34-22.23)、1.12(1.00-1.25)、1.22(1.12-1.34)、1.02(1.01-1.29)、1.18(1.06-1.31)].Conclusion The coverage rate of basic immunization against epidemic cerebrospinal meningitis among children aged from 6 to 35 months is relatively high.The focus of vaccination promotion can be placed on migrant children and rural areas,and the vaccination work in outpatient clinics serving small population can be strengthened to improve the basic immuniz

关 键 词：流脑疫苗 基础免疫 影响因素 

分 类 号：R186[医药卫生—流行病学]