瑞马唑仑复合舒芬太尼在老年患者胃肠镜诊疗镇静中的应用效果  

Application Effect of Remimazolam Combined with Sufentanil in Sedation of Elderly Patients During Gastroenteroscopy Diagnosis and Treatment

作　　者：赵媛媛 王涛 Zhao Yuanyuan;Wang Tao(Shandong Healthcare Group Laiwu Central Hospital,Jinan 271100,Shandong Province,China)

机构地区：[1]山东颐养健康集团莱芜中心医院,山东济南271100

出　　处：《中国社区医师》2025年第1期24-26,共3页Chinese Community Doctors

摘　　要：目的:探讨瑞马唑仑复合舒芬太尼在老年胃肠镜诊疗镇静中的应用效果。方法:选取2023年1月—2024年3月于山东颐养健康集团莱芜中心医院接受胃肠镜诊疗的86例老年患者进行研究,随机分为对照组和观察组,每组43例。两组患者均给予舒芬太尼麻醉,对照组在此基础上给予丙泊酚麻醉,观察组给予瑞马唑仑麻醉。比较两组精神状态评分、镇静效果、疼痛程度、不良反应发生率。结果:两组麻醉前简易精神状态量表(MMSE)评分比较,无统计学差异(P>0.05);苏醒15 min、30 min、60 min后,两组MMSE评分均低于麻醉前,但观察组高于对照组(P<0.05)。两组胃镜检查时间比较,无统计学差异(P>0.05);观察组苏醒时间、复苏室停留时间短于对照组,视觉模拟评分法评分低于对照组(P<0.05)。观察组不良反应总发生率低于对照组(P<0.001)。结论:瑞马唑仑复合舒芬太尼在老年患者胃肠镜诊疗镇静中的应用效果较好,能够缩短患者苏醒时间,促进其认知功能恢复,减轻疼痛,降低不良反应发生率。Objective:To explore the application effect of remimazolam combined with sufentanil in sedation of elderly patients during gastroenteroscopy diagnosis and treatment.Methods:A total of 86 elderly patients who underwent gastroenteroscopy diagnosis and treatment in Shandong Healthcare Group Laiwu Central Hospital from January 2023 to March 2024 were selected for the study.They were randomly divided into control group and observation group,with 43 cases in each group.Patients in both groups were anesthetized using sufentanil.On this basis,the control group was given propofol anesthesia,and the observation group was given remimazolam anesthesia.The mental status score,sedation effect,pain degree,and incidence of adverse reactions were compared between the two groups.Results:There was no statistically significant difference in the scores of the Mini-Mental State Examination scale(MMSE)between the two groups before anesthesia(P>0.05).After 15 min,30 min and 60 min of awakening,the MMSE scores in the two groups were lower than those before anesthesia,but the scores in the observation group were higher than those in the control group(P<0.05).There was no statistically significant difference in gastroscopy time between the two groups(P>0.05).The recovery time and resuscitation room stay time in the observation group were shorter than those in the control group,and the score of visual analogue scale in the observation group was lower than that in the control group(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.001).Conclusion:Remimazolam combined with sufentanil has a good effect in the sedation of elderly patients during gastroenteroscopy diagnosis and treatment,and can shorten the awakening time of patients,promote the recovery of cognitive function,relieve pain,and reduce the incidence of adverse reactions.

关 键 词：瑞马唑仑 丙泊酚 舒芬太尼 老年 胃肠镜 

分 类 号：R614[医药卫生—麻醉学]