慢性心力衰竭患者报告结局量表效标效度评价  

Evaluation of the Criterion Validity of the Patient-reported Outcome Measure for Chronic Heart Failure

作　　者：原娜 张青 杜宇涛 王钰婧 张岩波 田晶[2,3] Yuan Na;Zhang Qing;Du Yutao(Department of Health Statistics,School of Public Health,Shanxi Medical University,Taiyuan 030001)

机构地区：[1]山西医科大学公共卫生学院卫生统计学教研室,030001 [2]山西医科大学第一医院心内科 [3]重大疾病风险评估山西省重点实验室

出　　处：《中国卫生统计》2024年第6期857-861,共5页Chinese Journal of Health Statistics

基　　金：国家自然科学基金青年项目(82103958);山西省重点研发计划项目(201903D321104);山西省科技成果转化引导专项(202104021301063)。

摘　　要：目的评价慢性心力衰竭患者报告结局量表(patient-reported outcome measure for chronic heart failure,CHF-PROM)的同时效度和预测效度。方法对符合纳入排除标准的1128例慢性心力衰竭患者进行前瞻性队列随访。Pearson及Spearman用于分析同时效度的效标与CHF-PROM各领域评分和总分之间的相关性。将患者发生心衰再住院和死亡作为预测效度的效标,采用单因素和多因素两水平Cox回归模型分析CHF-PROM各领域评分和总分对患者再住院和死亡风险的影响。结果同时效度分析结果表明,生理领域评分、心理领域评分和总分与纽约心脏病协会(New York Heart Association,NYHA)心功能分级呈负相关,且生理领域评分与N末端B型利钠肽前体(N-terminal pro-B type natriuretic peptide,NT-proBNP)水平呈负相关。预测效度分析结果表明,生理领域评分是心衰患者再住院和死亡的预测因子,心理领域评分仅与患者再住院有关。结论CHF-PROM是用于评价CHF患者的有效工具。该量表具有良好的同时效度,且具有较好的预警能力。Objective To evaluate the concurrent validity and predictive validity of the patient-reported outcome measure for chronic heart failure(CHF-PROM).Methods A prospective cohort of 1128 patients with chronic heart failure who met the inclusion and exclusion criteria was followed.To analyze the correlation between the concurrent validity criterion and the CHF-PROM each field score and total score using Pearson and Spearman.As a predictive validity criterion,readmission and death from heart failure were used.Analyze the effects of CHF-PROM each field score and total score on the risk of readmission and death using univariate and multivariate two-level Cox regression models.Results The results of concurrent validity analysis showed that the physiological field score,psychological field score and total score were negatively correlated with the New York Heart Association(NYHA)class.Physiological field scores were inversely correlated with N-terminal pro-B type natriuretic peptide(NT-proBNP)levels.The results of predictive validity analysis showed that the physiological field score was a predictor of readmission and death in patients with heart failure,and the psychological field score was only related to patient readmission.Conclusion CHF-PROM is a valid tool to evaluate in patients with chronic heart failure.The scale has good concurrent validity and predictive power.

关 键 词：慢性心力衰竭 患者报告结局 效标效度 

分 类 号：R541.6[医药卫生—心血管疾病]