面向人体呼吸特征和气体组分精准控制的主动模拟肺研究  

Research of Active Lung Simulator for Human Respiratory Characteristics and Precise Control of Gas Composition

作　　者：祖明宇 马嵩华 胡天亮[1,2,3] 马德东 ZU Mingyu;MA Songhua;HU Tianliang;MA Dedong(School of Mechanical Engineering,Shandong University,Jinan,Shandong 250061;Key Laboratory of High Efficiency and Clean Mechanical Manufacture of the Ministry of Education,Jinan,Shandong 250061;National Demonstration Center for Experimental Mechanical Engineering Education,Jinan,Shandong 250061;Qilu Hospital of Shandong University,Jinan,Shandong 250012;Key Laboratory of Otolaryngology,Shandong University,Jinan,Shandong 250012)

机构地区：[1]山东大学机械工程学院,山东济南250061 [2]高效洁净机械制造教育部重点实验室,山东济南250061 [3]机械工程国家级实验教学示范中心,山东济南250061 [4]山东大学齐鲁医院,山东济南250012 [5]山东大学国家卫生健康委员会耳鼻喉科学重点实验室,山东济南250012

出　　处：《液压与气动》2025年第1期95-106,共12页Chinese Hydraulics & Pneumatics

基　　金：山东省重点研发计划(重大科技创新工程)(2023CXGC010508);泰山学者特别基金;山东大学齐鲁学者特别基金。

摘　　要：为配合呼吸机测试、临床人员培训和呼吸诊疗设备研发等工作,设计了一套主动模拟肺设备。介绍了该主动模拟肺设备的系统设计方案,使用电气比例阀作为执行部件,通过增量PI和模糊PID控制算法,调节每条支气路气体流量,实现对呼吸特征和气体组分的精确控制。对人体正常呼吸和麻醉呼吸模式下的呼吸动作进行模拟,流量曲线的跟随性较好,均方根误差在可接受阈值内,其潮气量、峰值流量等呼吸特征均达到要求;同时,该模拟肺对于气体组分的控制能够满足对血氧交换过程的模拟需求,代替人体完成面向不同类型呼吸疾病和不同病程的呼吸诊疗设备校验和调整。This study proposes an active lung simulator aimed at supporting ventilator testing,clinical personnel training,and the development of respiratory diagnostic and therapeutic devices.The system utilizes an electrical proportional valve as its actuator,with incremental PI and fuzzy PID control algorithms employed to regulate gas flow in each branch,achieving precise control of both respiratory features and gas composition.Experimental simulations of normal human breathing and anesthetic breathing patterns demonstrate that the active lung simulator achieves excellent flow curve tracking performance,with root mean square errors within acceptable thresholds.Key respiratory parameters,including tidal volume and peak flow rate,meet the required standards.Furthermore,the simulator effectively controls gas composition to mimic the blood gas exchange process,providing a reliable alternative for calibrating and adjusting respiratory therapeutic equipment for various respiratory diseases and stages of disease progression.

关 键 词：模拟肺 模糊PID 气体组分 电气比例阀 

分 类 号：TH138[机械工程—机械制造及自动化] TH772[自动化与计算机技术—检测技术与自动化装置] TH39[自动化与计算机技术—控制科学与工程] TP23