老年性耳聋发病机制及治疗进展  

Progress in Research on Pathogenesis and Treatment of Presbycusis

作　　者：李木兰 王述立 郑庆印[1] 马朋 LI Mulan;WANG Shuli;ZHENG Qingyin;MA Peng(Hearing and Speech Rehabilitation Institute,School of Special Education,Binzhou Medical University,Yantai 264003,China;不详)

机构地区：[1]滨州医学院特殊教育与康复学院听力与言语康复研究院,烟台264003 [2]滨州医学院基础医学院,烟台264003

出　　处：《中华耳科学杂志》2025年第1期124-127,共4页Chinese Journal of Otology

基　　金：山东省自然科学基金重点项目(ZR2020KH025)。

摘　　要：老年性耳聋是听觉器官衰退引起的听觉障碍,对老年人的健康有严重影响。其发病机制主要与氧化应激、炎症、激素水平、遗传因素和环境因素等有关。目前改善听力的方法局限于使用听觉辅助装置,药物治疗、基因和干细胞治疗还在基础研究阶段,或能成为新的治疗选择。本文归纳了老年性耳聋的部分发病机制和治疗进展。Presbycusis is a hearing disorder caused by degenerative changes of the auditory organ,which can have a serious impact on the health of the elderly.Its pathogenesis is mainly related to oxidative stress,inflammation,hormone levels,genetic factors and environmental risks.Current approaches to improving hearing are limited to hearing aids,and drug therapy,gene therapy and stem cell therapy are still in the stage of basic research,although some of them may become new treatment options in the future.This article summarizes the pathogenesis and therapeutic advances in age-related deafness.

关 键 词：老年性耳聋 发病机制 治疗 

分 类 号：R764.436[医药卫生—耳鼻咽喉科]