骨肿瘤化疗患者中重度癌因性疲乏发生状况及其影响因素分析  

The incidence and influence factors of moderate to severe cancer-related fatigue in bone tumor chemotherapy patients

作　　者：方国林 万昌丽 李晓林 欧艺轩 Fang Guolin;Wan Changli;Li Xiaolin;Ou Yixuan(Department of Bone Oncology,The Second Affiliated Hospital of Naval Medical University,Shanghai 200003,China.)

机构地区：[1]海军军医大学第二附属医院骨肿瘤科,上海200003

出　　处：《现代临床护理》2024年第12期23-28,共6页Modern Clinical Nursing

基　　金：上海市科委项目,项目编号为23Y11903600。

摘　　要：目的调查骨肿瘤化疗患者中重度癌因性疲乏发生状况,并分析其影响因素。方法采用便利抽样法,选取2021年1月至2023年6月本院首次接受化疗的265例骨肿瘤患者作为研究对象,采用一般资料调查表、Piper疲乏量表(the revised piper fatigue scale,PFS-R)、汉密尔顿焦虑量表、汉密尔顿抑郁量表和简易应对方式问卷进行调查,并采用Logistic回归分析骨肿瘤化疗患者癌因性疲乏状态的影响因素。结果239例患者完成研究。骨肿瘤化疗患者中重度癌因性疲乏154例,发生率为64.44%。Logistic回归分析显示,每日睡眠时间<5h,体质量指数较低及焦虑、抑郁评分较高是骨肿瘤化疗患者癌因性疲乏的危险因素,积极应对方式是其保护因素(均P<0.05)。结论骨肿瘤化疗患者中重度癌因性疲乏发生率较高,需针对体质量指数较低、睡眠时间较短、焦虑、抑郁情绪以及消极应对方式的患者预干预,从而减少患者中重度癌因性疲乏的发生。Objective To investigate the incidence of moderate to severe cancer-related fatigue in bone tumor chemotherapy patients and its influence factors were analyzed.Methods Totally 265 bone tumor chemotherapy patients who received chemotherapy for the first time in our hospital from January 2021 to June 2023 were selected as the research subjects by convenience sampling method.A general information survey Hamilton anxiety scale,Hamilton depression scale,simplified coping style questionnaire and the Piper fatigue scale revised(PFS-R)were used to investigate the cancer-related fatigue status of bone tumor chemotherapy patients,and the logistic regression analysis was used to analyze its influencing factors.Results Totally 239 patients completed the study.Among 239 bone tumor chemotherapy patients,154 cases had moderate to severe cancer-related fatigue,the incidence rate was 64.44%.The Logistic regression analysis showed that daily sleep time<5 hours,low body weight,and high anxiety and depression scores were risk factors for moderate to severe cancer-related fatigue in bone tumor chemotherapy patients,while active coping strategies was protective factors(all P<0.05).Conclusion The incidence of moderate to severe cancer-related fatigue in bone tumor chemotherapy patients is relatively high.Preintervention is needed for patients with low body weight,short sleep time,anxiety,depression,and negative coping strategies to reduce the occurrence of moderate to severe cancer-related fatigue in patients.

关 键 词：骨肿瘤 化疗 癌性疲乏 中重度 影响因素 横断面研究 

分 类 号：R473.73[医药卫生—护理学]