小儿咳嗽糖浆佐治婴幼儿百日咳综合征的疗效观察  

Observation on the curative effect of Paediatric Cough Syrup in treating infants with pertussis syndrome

作　　者：曾祥妮 李岚[1] 万彩红 吴爱民[1] 黄鹏 ZENG Xiangni;LI Lan;WAN Caihong;WU Aimin;HUANG Peng(Department of Respiratory Medicine,Jiangxi Provincial Children's Hospital,Jiangxi Province,Nanchang 330006,China)

机构地区：[1]江西省儿童医院呼吸内科,江西南昌330006

出　　处：《中国当代医药》2025年第2期63-66,共4页China Modern Medicine

基　　金：江西省中医药管理局科技计划项目(2022B485);江西省科技计划项目(20171BBG70020)。

摘　　要：目的探讨小儿咳嗽糖浆对婴幼儿百日咳综合征的治疗效果,以期为此类疾病的临床诊治提供有价值的参考和指导。方法回顾性分析2023年1月至2024年1月江西省儿童医院收治的69例百日咳综合征的婴幼儿的临床资料,根据治疗方法不同分为观察组(32例)和对照组(37例),观察组接受常规治疗联合小儿咳嗽糖浆治疗,对照组仅接受常规治疗。比较两组患儿痉挛性咳嗽消失时间、咳痰明显减少时间、肺部啰音吸收时间及住院时间、治疗5 d后总有效率及入院第3天和第5天日间咳嗽评分,评估小儿咳嗽糖浆的治疗效果。结果两组患儿的住院天数比较,差异无统计学意义(P>0.05)。观察组痉挛性咳嗽消失时间、咳痰明显减少时间、肺部啰音吸收时间短于对照组,差异有统计学意义(P<0.05),两组患儿在入院后第3天时的咳嗽评分比较,差异无统计学意义(P>0.05)。入院后第5天,观察组的咳嗽评分低于对照组,差异有统计学意义(P<0.05)。两组入院后第5天咳嗽评分均低于本组入院后第3天,差异有统计学意义(P<0.05)。两组均未出现不良反应。结论小儿咳嗽糖浆作为辅助治疗手段,在百日咳综合征婴幼儿患者的治疗中能够有效改善患儿症状,提高治疗效果,为临床诊治提供了有益的补充。Objective To explore the therapeutic effect of Pediatric Cough Syrup on pertussis syndrome in order to provide valuable reference and guidance for the clinical diagnosis and treatment of this disease.Methods The clinical data of 69 infants with pertussis syndrome admitted to the Jiangxi Provincial Children's Hospital from January 2023 to January 2024 were retrospectively analyzed,and they were divided into observation group(32 cases)and control group(37 cases)according to different treatment.The observation group received conventional treatment combined with Paediatric Cough Syrup,while the control group received conventional treatment only.To evaluate the therapeutic effect of Pediatric Cough Syrup,the time of spastic cough disappearance,the time of significantly less expectoration,the time of lung rale absorption and the length of hospital stay were compared between the two groups,and the total effective rate after 5 days of treatment and the daytime cough score on the 3rd and 5th day of admission.Results There was no significant difference in length of hospital stay between the two groups(P>0.05).The time for spastic cough to disappear,the time for sputum to decrease significantly,and the time for lung rales absorption in the observation group were shorter than those in the control group,with statistical significances(P<0.05).There were no statistical significances in the cough scores of the two groups on the 3rd day after admission(P>0.05).On the 5th day,the cough score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).The cough scores of the two groups on the 5th day after admission were lower than those on the 3rd day after admission,and the differences were statistically significant(P<0.05).There were no adverse reactions in both groups.Conclusion Pediatric Cough Syrup,as an auxiliary treatment means,can effectively improve the symptoms of infants with pertussis syndrome,improve the therapeutic effect,and provide a beneficial suppleme

关 键 词：小儿咳嗽糖浆 百日咳综合征 婴幼儿 疗效观察 

分 类 号：R516.6[医药卫生—内科学]