北京市门头沟区王平镇利什曼原虫感染情况预调查  

PRELIMINARY INVESTIGATION OF LEISHMANIA INFECTIONIN WANGPING STREET MENTOUGOU DISTRICT, BEIJING

作　　者：李兴隆 王志越[2] 何占英[3] 王小梅[3] 吴文婷 史瑞崎 LI Xing-long;WANG Zhi-yue;HE Zhan-ying;WANG Xiao-mei;WU Wen-ting;SHI Rui-qi(Junzhuang Town Community Healthcare Center,Beijing Mentougou District,Beijing 102300,China;Mentougou Center for Disease Control and Prevention,Beijing 102300,China;Beijing Center for Disease Control and Prevention,Beijing 100013,China)

机构地区：[1]北京市门头沟区军庄镇社区卫生服务中心,北京102300 [2]北京市门头沟区疾病预防控制中心,北京102300 [3]北京市疾病预防控制中心,北京100013

出　　处：《寄生虫与医学昆虫学报》2024年第4期199-202,208,共5页Acta Parasitologica et Medica Entomologica Sinica

摘　　要：目的 了解北京市门头沟区王平镇利什曼原虫在白蛉、犬以及人群中的感染率,为门头沟区黑热病的防控提供决策依据。方法 2021年4月上旬至11月下旬在患者活动区域周边捕获白蛉,在全区范围内搜索疑似病犬并采集全血,在患者活动区域随机采集本地居民全血,所有样本进行利什曼原虫感染相关检测。结果 共捕获白蛉4 280只,所有白蛉研磨后进行PCR检测,均未检出利什曼原虫相关核酸片段;采集疑似病犬36只,其中9只疑似病犬rk39试纸条结果显示利什曼原虫抗体阳性,PCR复测利什曼原虫核酸阳性;患者活动区域周边人群共采集73人份血液标本,使用rk39试纸条检测利什曼原虫抗体,检测结果均呈阴性,未进行PCR复测。结论 门头沟区王平镇目前有可能正处于犬源型黑热病犬内流行期,若不及时控制,有可能进展至人群流行期。Objective This study aimed to understand the infection rates of Leishmania parasites in sandflies,dogs,and humans in Wangping Street,Mentougou District,Beijing,to provide decision-making recommendations for the prevention and control of the Leishmania infection(Kala-Azar).Methods From early April to late November 2021,sandflies were trapped to screen for Leishmania parasites using Leishmania-specific PCR in Mentougou District,Beijing.Simultaneously,residents and suspected dogs were tested to detect possible Leishmania infections using the rk39 immunochromatographic test strip and Leishmania-specific PCR tests.Results A total of 4280 Phlebotomus chinensis were captured from Mentougou District and no Leishmania parasites were detected.Nine of 36 suspected sick dogs tested positive for Leishmania parasites.No positive human blood samples were obtained from the 73 residents around the index patient's activity area.Conclusions A canine Kala-Azar outbreak occurred in Wangping town.Timely surveillance and control measures are urgently needed in the Mentougou District.

关 键 词：利什曼原虫 白蛉 黑热病 门头沟区 北京 

分 类 号：R382.2[医药卫生—医学寄生虫学]