癌“浊”理论现代科学内涵及中医证治思辨  

Modern scientific connotations of cancer"turbidity"theory and speculation on its TCM syndrome differentiation and treatment

作　　者：刘秀娟[1] 胡凯文[2] 王舒扬 张水秀 王婧筱 LIU Xiujuan;HU Kaiwen;WANG Shuyang;ZHANG Shuixiu;WANG Jingxiao(Beijing University of Chinese Medicine,Beijing 100029,China;Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100078,China;School of Life Sciences,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学东方医院,北京100078 [3]北京中医药大学生命科学学院,北京102401

出　　处：《吉林中医药》2025年第1期1-5,共5页Jilin Journal of Chinese Medicine

基　　金：国家重点研发计划项目(2018YC1705100);国家自然科学基金项目(82104651,82174231);北京市科技新星计划(2022041);北京市科委、中关村管委会AI+健康协同创新培育项目(Z221100003522029)。

摘　　要：“浊”邪在“积聚”“癥瘕”“脏结”等肿瘤疾病的发生发展过程中起重要作用。从“浊”之发源、癌“浊”理论形成及“浊”邪现代科学内涵对癌“浊”理论进行深入阐释,总结出与肿瘤发生发展关系密切的异常累积代谢产物。胡凯文教授认为癌“浊”的产生与气机升降出入关系密切,内生五邪、外感六淫引起的体内气机升降失司,水液代谢失调,日久化为“浊”邪,并可与痰、瘀、毒等多种病理产物兼见。胡凯文通过调节气机升降纠正癌“浊”,提出良性、恶性肿瘤治疗化浊、散浊之法,主要治疗策略为癌浊凝滞、气机不降当化浊降气,痰浊郁结、气机不升当散浊宣郁,以期为中医临床治疗肿瘤提供参考。Turbidity plays an important role in the occurrence and development of tumor diseases,such as"amassment and accumulation","abdominal masses",and"binding of zang-viscera".In this paper,the origin of"turbidity",the formation of cancer"turbidity"theory and the modern scientific connotations of"turbidity"are explored,and the abnormal accumulated metabolites which are closely related to the occurrence and development of cancer are summarized.Professor Hu Kaiwen believes that the generation of"turbidity"in cancer is closely related to the ascending,descending,exiting and entering of qi flow,in which endogenous five pernicious factors and exogenous six pathogenic factors cause the dysfunction of qi movement and disharmony of water and fluids metabolism,transforming into"turbidity"over time and possibly combining with various pathological products such as phlegm,blood stasis,and toxin.He regulates cancer"turbidity"by adjusting the rise and fall of qi movement,putting forward the methods of eliminating turbidity and dispersing turbidity in the treatment of benign and malignant tumors.His main treatment strategies involve eliminating turbidity to descend qi and dispersing turbidity to improve qi stagnation.The paper is expected to provide a reference for the clinical treatment of tumors in traditional Chinese medicine.

关 键 词：浊邪 代谢产物 肿瘤 中医辨证 

分 类 号：R273[医药卫生—中西医结合]