基于态靶理论的子宫肌瘤治疗方略探析  

An analysis of treatment strategies for uterine fibroids based on the state-target theory

作　　者：征征 张莉莉[1] 赵林华[1] 刘新敏[1] ZHENG Zheng;ZHANG Lili;ZHAO Linhua;LIU Xinmin(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]中国中医科学院广安门医院,北京100053

出　　处：《吉林中医药》2025年第1期6-9,共4页Jilin Journal of Chinese Medicine

基　　金：国家自然科学基金项目(81674011);中国中医科学院科技创新工程重大攻关项目(CI2021A02404)。

摘　　要：子宫肌瘤发病机制尚不明确。态靶理论是仝小林院士基于多年临证经验提出的现代中医诊疗范式,适用于多种慢性疾病的诊疗。根据态靶理论,认为子宫肌瘤当以瘀态贯穿始终,于瘀态之下细述证治方药,其中,气滞血瘀证予四逆散合膈下逐瘀汤;寒凝血瘀证予少腹逐瘀汤加三棱、莪术;痰瘀互结证予苍附导痰丸合桂枝茯苓丸;气虚血瘀证予理冲汤。列举针对患者不同症状及指标的靶药,如经行小腹胀痛,可加厚朴、元胡、乌药;经行小腹冷痛,可加肉桂、炮姜;贫血者,可加生黄芪、党参、当归等。Uterine fibroid is the most common gynecological benign tumor,with high incidence,high detection rate and high recurrence rate.Its main clinical manifestations involve abdominal mass,heavy menstruation and prolonged menstruation,while its pathogenesis remains unclear.The state-target theory is a modern TCM diagnosis and treatment paradigm proposed by Academician Tong Xiaolin based on his many years of clinical experience,which is applicable to the diagnosis and treatment of a variety of chronic diseases.In this paper,according to the theory of state-target,it is speculated that a stasis state is present in uterine fibroid throughout its whole course,and the specific syndromes,treatment methods,prescriptions and medications for the disease should be discerned and formulated at length under this state.Specifically,the syndrome of qi stagnation and blood stasis should be treated with Sini powder plus Gexia Zhuyu decoction,while the syndrome of cold coagulation and blood stasis should be treated with Shaofu Zhuyu decoction plus common buried rubber,zedoary rhizome,and the syndrome of intermingled phlegm and blood stasis should be treated with Cangfu Daotan pills combined with Guizhi Fuling pills,while the syndrome of blood stasis due to qi deficiency should be treated with Lichong decoction.Besides,the target drugs for patients with different symptoms and indicators are listed as examples,such as for symptom of lower abdominal distention and pain during menstruation,officinal magnolia bark,Yuanhu and combined spicebush root can be added to prescriptions,while for symptom of cold pain in the lower abdomen,cassia bark and processed ginger can be utilized,and for symptom of anemia,fresh milkvetch root,tangshen,Chinese angelica and so on can be selected.The theory of statetarget is supposed to reveal the pathogenesis of uterine fibroids in this study.

关 键 词：子宫肌瘤 态靶理论 中药 

分 类 号：R271.9[医药卫生—中西医结合]