头穴丛刺针法联合认知功能训练治疗轻中度血管性痴呆  

Therapeutic effect of head point cluster needling combined with cognitive function training in the treatment of mild to moderate vascular dementia

作　　者：夏帆 陈小华[1] 钟静雅 明康文 XIA Fan;CHEN Xiaohua;ZHONG Jingya;MING Kangwen(Department of Acupuncture and Moxibustion Rehabilitation,Affiliated Guangzhou Hospital of Traditional Chinese Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510130,China;Department of Acupuncture and Moxibustion Rehabilitation,Affiliated Hospital of Traditional Chinese Medicine,Guangzhou Medical University,Guangzhou 510130,China)

机构地区：[1]广州中医药大学附属广州中医医院针灸康复科,广州510130 [2]广州医科大学附属中医医院针灸康复科,广州510130

出　　处：《吉林中医药》2025年第1期109-112,共4页Jilin Journal of Chinese Medicine

基　　金：广东省中医药局科研项目(20221318)。

摘　　要：目的观察头穴丛刺针法联合认知功能训练治疗轻中度血管性痴呆的临床疗效结果及对患者认知功能障碍、行为能力、痴呆程度的影响。方法选择86例轻中度血管性痴呆患者,按随机数表法分为对照组与治疗组,各43例。对照组予认知功能训练治疗,治疗组在对照组基础上予头穴丛刺针法治疗。2组疗程均为8周。比较2组临床疗效,治疗前后简易精神智能状态量表(MMSE)评分,Blessed行为量表评分,临床痴呆评定量表(CDR)评分,脑血流动力学指标脑动脉的收缩期峰值血流速度(Vm)、平均血流速度(Vs)、脉动指数(PI),血清脑神经因子血清神经生长因子(NGF)、脑源性神经营养因子(BDNF)水平变化。结果治疗组临床疗效总有效率(83.7%,36/43)显著高对照组(62.8%,27/43)(P<0.05);治疗后,2组MMSE评分,Vm和Vs指标,血清NGF和BDNF水平均高于治疗前(P<0.05),且治疗组高于对照组(P<0.05);2组Blessed评分、CDR评分均低于治疗前(P<0.05),治疗组低于对照组(P<0.05);治疗组PI指标低于治疗前(P<0.05),对照组PI指标与治疗前比较,差异无统计学意义(P<0.05)。结论头穴丛刺法联合认知功能训练治疗轻中度血管性痴呆患者,能够有效调节血清脑神经因子水平,改善脑血流动力学指标,提高认知功能障碍,缓解痴呆程度。Objective To observe the therapeutic effect of head point cluster needling combined with cognitive function training in the treatment of mild to moderate vascular dementia and its impacts on patients’cognitive dysfunction,behavioral ability,and dementia degree.Methods A total of 86 patients with mild to moderate vascular dementia were selected for the study and randomly divided into two groups,with 43 cases in each group.The control group received a cognitive function training,while the treatment group received a head point cluster acupuncture treatment on the basis of the control group.Both groups underwent a treatment period of 8 weeks.The clinical efficacy,changes in the Mini Mental State Scale(MMSE)scores,Blesed Behavior Scale scores,Clinical Dementia Rating Scale(CDR)scores,cerebral hemodynamic indicators[peak systolic blood flow velocity(Vm),mean blood flow velocity(Vs),pulsatility index(PI)of cerebral arteries],and serum levels of brain neurotrophic factors[serum nerve growth factor(NGF),brain-derived neurotrophic factor(BDNF)]were compared between the two groups of patients before and after treatment.Results The total effective rate of the treatment group was 83.7%,significantly higher than that of the control group at 62.8%(P<0.05).The MMSE scores,Vm and Vs indicators,serum NGF and BDNF levels were significantly higher after treatment in the two groups(P<0.05),and the levels of these indicators were significantly higher in the treatment group than those in the control group(P<0.05).After treatment,the Blessed scores,CDR scores were significantly lower than before treatment in the two groups(P<0.05),and the levels of the above indicators were significantly lower in the treatment group than those in the control group(P<0.05).After treatment,the PI index in the treatment group showed a significant decrease(P<0.05),while there was no significant difference in it in the control group(P>0.05).Conclusion The head point cluster needling can regulate the serum levels of cranial nerve factors in patients with mi

关 键 词：轻中度血管性痴呆 头穴丛刺针法 认知功能训练 认知功能障碍 行为能力 痴呆程度 

分 类 号：R246[医药卫生—针灸推拿学]