Q‑value customized versus wavefront‑optimized ablation in femtosecond laser‑assisted LASIK for myopia and myopic astigmatism:a prospective contralateral comparative study  

作　　者：Magdi Mohammad Mostafa Hazem Abdelmotaal Khaled Abdelazeem Islam Goda Mahmoud Abdel‑Radi 

机构地区：[1]Department of Ophthalmology,Assiut University Hospital,Assiut University,Sixth Floor,Assiut 71516,Egypt

出　　处：《Eye and Vision》2024年第6期20-32,共13页眼视光学杂志(英文)

摘　　要：Background:Corneal refractive surgery for myopia results in an oblate shift with increased postoperative aberrations inversely affecting the quality of vision.Aspheric ablation profiles have been introduced to minimize such a problem.The aim of this study was to compare changes in corneal asphericity,central and mid-peripheral pachymetry between the Q-value customized and the wavefront-optimized(WFO)ablation profiles.Methods:A prospective,comparative non-randomized fellow eye study was conducted.Eighty eyes of 40 eligible patients underwent femtosecond laser-assisted laser in situ keratomileusis for myopia and myopic astigmatism.In each patient,the more myopic eye was included in the custom-Q ablation experimental group and the other less myopic eye was included in the WFO control group.For the custom-Q group,the target asphericity was set to the preoperative Q-value.Corneal asphericity,central and mid-peripheral pachymetric changes and the root mean square of corneal higher-order aberrations(RMSh)were assessed 6 months following surgery.Visual and refractive outcomes were also evaluated in both platforms 6 months postoperatively.Results:The mean preoperative refractive spherical equivalent was significantly more myopic in the custom-Q group than in the WFO group(P=0.001).The mean Q-value changed from−0.2±0.1 to 0.6±0.7 and from−0.2±0.1 to 0.4±0.5 in the custom-Q and WFO groups,respectively.The oblate shift in corneal asphericity was not significantly different between both treatment groups(P=0.094).The mean ablation depth at the pupillary center was significantly greater in the custom-Q group(P=0.011),while there was no significant difference at the mid-peripheral pachymetry(P=0.256).The RMSh significantly increased in both treatment profiles(P<0.001)with no significant difference between the two groups(P=0.06).The uncorrected distance visual acuity(UDVA)and the manifest refraction spherical equivalents(MRSE)significantly improved in both treatment groups(P<0.001).Conclusions:The custom-Q treatment profi

关 键 词：Custom Q Wavefront-optimized Corneal asphericity Q-VALUE 

分 类 号：TG2[金属学及工艺—铸造]