振幅整合脑电图联合颅脑超声对早产儿脑损伤的评估分析  

Assessment and analysis of brain injury in premature infants using amplitude-integrated electroencephalography combined with cranial ultrasound

作　　者：万元[1] 李亚林[1] 喻月 WAN Yuan;LI Yalin;YU Yue(Department of Neonatology,Xuancheng People's Hospital,Xuancheng 242000,China)

机构地区：[1]安徽省宣城市人民医院新生儿科,安徽宣城242000

出　　处：《医学影像学杂志》2024年第12期10-13,共4页Journal of Medical Imaging

基　　金：安徽省自然科学基金项目(编号:2008085QH221)。

摘　　要：目的探讨将振幅整合脑电图与颅脑超声联合评估早产儿脑损伤的价值。方法选取本院救治的早产儿70例临床资料,根据临床诊断脑损伤23例(32.86%),无脑损伤47例(67.14%);以临床诊断为金标准,通过一致性分析探讨颅脑超声与振幅整合脑电图单独及联合检查对早产儿脑损伤的评估效能。结果颅脑超声、振幅整合脑电图单独及联合评估早产儿脑损伤结果与金标准的一致性分别为0.776、0.498、0.843,振幅整合脑电图联合颅脑超声评估一致性最好;振幅整合脑电图联合颅脑超声诊断早产儿脑损伤的准确度、灵敏度整体优于振幅整合脑电图、颅脑超声单独诊断,差异有统计学意义(P<0.05)。结论将颅脑超声、振幅整合脑电图两种方法联合应用,可提高对早产儿是否发生脑损伤的评估效能,可为临床评估患儿脑损伤发生风险和及时发现早期脑损伤提供帮助。Objective To explore the value of combining amplitude-integrated electroencephalogram(EEG)and cranial ultrasound in evaluating brain injury in premature infants.Methods Clinical data of 70 preterm infants treated in our hospital were selected.According to clinical diagnosis,23 cases(32.86%)had brain injury and 47 cases(67.14%)had no brain injury.With clinical diagnosis as the gold standard,the efficacy of craniocerebral ultrasound and amplitude-integrated electroencephalography(EEGS)alone and combined in the evaluation of brain injury in premature infants was investigated by consistency analysis.Results The consistency between the evaluation of premature infant brain injury using cranial ultrasound and amplitude-integrated electroencephalography alone and in combination with the gold standard was 0.776,0.498,and 0.843,respectively.The combination of amplitude-integrated electroencephalography and cranial ultrasound had the best consistency.The accuracy and sensitivity of amplitude-integrated electroencephalography combined with cranial ultrasound in diagnosing brain injury in premature infants were generally better than those of amplitude-integrated electroencephalography and cranial ultrasound alone(P<0.05).Conclusion The combined application of cranial ultrasound and amplitude-integrated EEG can improve the evaluation efficiency of brain injury in premature infants,which can provide help for clinical evaluation of the risk of brain injury in children and timely detection of early brain injury.

关 键 词：早产儿 脑损伤 振幅整合脑电图 超声检查 

分 类 号：R722.6[医药卫生—儿科] R445.1[医药卫生—临床医学]