pH敏感型催化剂在不对称Aldol反应中的可控催化研究  

Controlled Catalysis of the pH-sensitive Catalyst for Asymmetric Aldol Reaction

作　　者：范艺萌 孙楠[1] 崔雪晴 徐小欢 孙继红[1] FAN Yimeng;SUN Nan;CUI Xueqing;XU Xiaohuan;SUN Jihong(Beijing University of Technology,Beijing 100124,China)

机构地区：[1]北京工业大学,北京100124

出　　处：《山东化工》2025年第1期49-51,共3页Shandong Chemical Industry

摘　　要：以介孔二氧化硅材料为核,聚丙烯酸为壳,手性联吡啶脯氨酸衍生物作为活性物种制备出具有pH智能响应性的催化剂(P-Z@BMMs)。将该催化剂应用于不对称Aldol反应进一步研究其可控催化性能,并采用HPLC分析手段对其催化性能进行表征。催化结果表明:P-Z@BMMs催化剂在不同pH值的复合有机溶剂中表现出良好的“智能开关”作用。The pH-responsive catalyst(P-Z@BMMs)was prepared with mesoporous silica material as the core,polyacrylic acid as the shell,and chiral bipyridine proline derivatives as the active species.The catalyst was applied to the Asymmetric Aldol reaction to further study its controllable catalytic performance,and its catalytic performance was characterized by HPLC analytical methods.The catalytic result showed that the P-Z@BMMs catalyst had a good"smart switch"effect in the composite organic solvents with different pH values.

关 键 词：NH2表面修饰介孔SiO_(2) 接枝PAA壳 不对称ALDOL反应 智能响应催化剂 核壳结构 手性联吡啶脯氨酸衍生物 

分 类 号：TQ426.6[化学工程]