Early prediction cardiac arrest in intensive care units:the value of laboratory indicator trends  

作　　者：Wentao Sang Jiaxin Ma Xuan Zhang Shuo Wu Chang Pan Jiaqi Zheng Wen Zheng Qiuhuan Yuan Jian Zhang Jingjing Ma Feng Xu 

机构地区：[1]Department of Emergency Medicine,Qilu Hospital,Shandong University,Jinan 250012,China [2]Chest Pain Center,Qilu Hospital,Shandong University,Jinan 250012,China [3]Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine,Institute of Emergency and Critical Care Medicine of Shandong University,Qilu Hospital,Shandong University,Jinan 250012,China [4]Key Laboratory of Emergency and Critical Care Medicine of Shandong Province,Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province,Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine,Qilu Hospital,Shandong University,Jinan 250012,China [5]Key Laboratory of Cardiovascular Remodeling and Function Research,Chinese Ministry of Education,Chinese Ministry of Health and Chinese Academy of Medical Sciences,the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine,Qilu Hospital,Shandong University,Jinan 250012,China

出　　处：《World Journal of Emergency Medicine》2025年第1期67-70,共4页世界急诊医学杂志(英文)

基　　金：supported by grants from the Key R&D Program of Shandong Province (2021ZLGX02);the National Science Foundation of China (81901934, 82325031);the National Key R&D Program of China (2020YFC1512700, 2020YFC1512705, 2020YFC1512703);the Clinical Research Center of Shandong University (2020SDUCRCC025)。

摘　　要：The incidence of in-hospital cardiac arrest (IHCA) has increased over the past decade,with more than half occurring in intensive care units (ICUs).^([1])ICU cardiac arrest (ICU-CA)presents unique challenges,with worse outcomes than those in monitored wards,highlighting the need for early detection and intervention.^([2])Up to 80%of patients exhibit signs of deterioration hours before IHCA.^([3])Although early warning scores based on vital signs are useful,their eff ectiveness in ICUs is limited due to abnormal physiological parameters.^([4])Laboratory markers,such as sodium,potassium,and lactate,are predictive of poor outcomes,^([5])but static measurements may not capture the patient’s trajectory.Trends in laboratory indicators,such as variability and extremes,may offer better predictive value.^([6])This study aimed to evaluate ICU-CA predictive factors,with a focus on vital signs and trends of laboratory indicators.

关 键 词：prediction SIGNS ARREST 

分 类 号：G63[文化科学—教育学]