Eosinophilia and clonorchiasis presenting as fever of unknown origin in adult patients  

作　　者：Jie Zhong Xin Zhou Wei Gu 

机构地区：[1]Department of Emergency Medicine,Chuiyangliu Hospital,Beijing 100022,China

出　　处：《World Journal of Emergency Medicine》2025年第1期91-93,共3页世界急诊医学杂志(英文)

摘　　要：Fever of unknown origin(FUO)is recognized as fever with uncertain diagnosis despite three days of hospital admission or three or more outpatient visits.[1]Acute liver fluke infection is characterized by fever,right upper quadrant pain,hepatomegaly,jaundice,and peripheral blood eosinophilia.By contrast,chronic liver fluke infection is asymptomatic in its early stage,but can easily progress to cirrhosis,cancer,or bile duct cancer initslaterstages.The diagnosis of clonorchiasis is particularly challenging in non-endemic areas.We herein report an unusual case of liver fluke infection in a patient who presented with FUO and eosinophilia.A 38-year-old male was admitted to our hospital with a history of intermittent and recurrent fever for over 10 d and a history of sudden abdominal pain for1 h.He had no other medical history.More than 10d ago,he visited our emergency department because of FUO,with his body temperature reaching 39.7℃,and he had no other symptoms at that time.Laboratory and radiological examinations revealed:white blood cell(WBC)counts,10.9×10^(9)/L;neutrophil percentage,84.5%;eosinophil percentage,3.1%;C-reactive protein(CRP),141 mg/L;liver and kidney function,normal;influenza virus,negative;urine and stool tests,normal;and chest computed tomography(CT)findings,normal.The fever subsided after 1 week of anti-infective treatment with moxifloxacin.Subsequent tests revealed the following results:WBC,15.0×10^(9)/L;neutrophil percentage,70.0%;eosinophil percentage,16.8%;and CRP,122 mg/L.The antimicrobial treatment was then discontinued.

关 键 词：FEVER DIAGNOSIS admitted 

分 类 号：R44[医药卫生—诊断学]