母乳微生态与新生儿免疫的研究进展  

Advances in breast milk microecology and neonatal immunity

作　　者：彭蕾 刘倩 王颖 范秀芳 李霞 Peng Lei;Liu Qian;Wang Ying;Fan Xiufang;Li Xia(NICU,Jinan Maternity and Child Care Hospital Afiliated to Shandong First Medical University,Jinan 250001,China)

机构地区：[1]山东第一医科大学附属济南妇幼保健院NICU,250001

出　　处：《国际儿科学杂志》2024年第12期819-823,共5页International Journal of Pediatrics

基　　金：济南市卫生健康委员会科技计划项目(2022-2-133)。

摘　　要：母乳作为新生儿最重要的营养物质来源,不仅富含蛋白质、脂肪、碳水化合物、维生素、矿物质等营养成分,还包含数百种生物活性因子,如激素、细胞因子、白细胞、免疫球蛋白、乳铁蛋白、溶菌酶、干细胞、母乳低聚糖、微生物群和微小RNA。母乳各组分综合作用,可调控新生儿免疫系统发育。其中,母乳中各种微生物相互作用,共同组成母乳微生态系统。母乳微生物群对新生儿免疫系统的发育促进作用越来越受重视,该文对母乳微生态与新生儿免疫构建的关系进行综述。As the most important source of nutrients for newborns,breast milk is not only rich in protein,fat,carbohydrates,vitamins,minerals and other nutrients,but also contains hundreds of bioactive factors,such as hormones,cytokines,white blood cells,immunoglobulins,lactoferrin,lysozyme,stem cells,breast milk oligosaccharides,micropopulation and microRNA.The comprehensive action of all components of breast milk can regulate the development of neonatal immune system.Various microorganisms in breast milk interact with each other to form a breast milk microecosystem.More and more attention has been paid to the role of breast milk microflora in promoting the development of neonatal immune system.This article reviews the relationship between breast milk microecology and neonatal immune function.

关 键 词：母乳 微生态 新生儿 免疫 

分 类 号：R72[医药卫生—儿科]