中老年人群CMM患病情况调查及CMM患者认知功能的关联因素分析  

Prevalence of cardiometabolic multimorbidity(CMM)in Chinese middle-aged and elderly population and the associated factors of cognitive function in CMM patients

作　　者：冯文婷 潘晔 史威力 刘志辉 淡亮星 王留义 Feng Wenting;Pan Ye;Shi Weili;Liu Zhihui;Dan Liangxing;Wang Liuyi(Department of General Practice,Henan Provincial People′s Hospital(People′s Hospital of Zhengzhou University),Zhengzhou450003,China;Information Section,Henan Integrative Medicine Hospital,Zhengzhou450003,China)

机构地区：[1]河南省人民医院(郑州大学人民医院)全科医学科,郑州450003 [2]河南省中西医结合医院信息科,郑州450003

出　　处：《中华全科医师杂志》2025年第1期62-69,共8页Chinese Journal of General Practitioners

基　　金：河南省医学科技攻关计划联合共建项目(RKX202101001);河南省中医药科学研究专项课题(2023ZYZD13)。

摘　　要：目的探讨我国中老年人群代谢性心血管共病(CMM)患病情况及CMM患者认知功能的关联因素。方法该研究为横断面研究, 选取Harmonized CHARLS D版本中2015年的被访者为研究对象, 排除其中仅患有情感和精神方面疾病及与记忆相关疾病的患者, 并排除慢性病患病数据缺失者。首先, 按照是否患有CMM对纳入人群进行分组, 分析中老年人群患CMM的关联因素。然后, 进一步在CMM患者中分析其认知功能的关联因素。收集纳入人群的一般临床资料。采用广义线性回归模型分析人口学特征、生活方式等与中老年人群CMM患病的关联, 以及上述因素与CMM患者认知功能评分的关联。结果共纳入15 007名被访者, 年龄(61.07±9.70)岁, 男性7 338名(48.9%), 3 303人(22.01%)患有CMM, 其中女性占比54.9%(1 814/3 033), 男性占比45.1%(1 489/3 033)。广义线性回归分析结果显示, 年龄、文化程度、居住地、抑郁症状与中老年CMM患者认知功能评分存在关联(均P<0.05)。结论我国中老年人群CMM患病率较高, 年龄、文化程度、居住地、抑郁症状与中老年CMM患者认知功能存在关联。Objective To investigate the prevalence of cardiometabolic multimorbidity(CMM)in Chinese middle-aged and elderly population,and the associated factors of cognitive function in CMM patients.MethodsIt was a cross-sectional study.Data of demographic characteristics,lifestyle,chronic disease,and cognitive function in middle-aged and elderly subjects were obtained from the Harmonized CHARLS D version 2015 database,subjects with emotional and psychiatric disorders and memory-related disorders,and those with missing chronic disease data were excluded.The factors associated with cognitive function in CMM patients were analyzed with generalized linear regression model.ResultsA total of 15007 respondents aged(61.07±9.70)years were included in the analysis,7338(48.9%)of whom were males.There were 3303 cases of CMM with a prevalence rate of 22.01%,and the proportion of females was 54.9%(1814/3033),and the proportion of males was 45.1%(1489/3033).Generalized linear regression analysis showed that age,educational level,place of residence,depressive symptoms were correlated with cognitive function scores of CMM patients(all P<0.05).ConclusionThe prevalence rate of CMM in middle-aged and elderly people in China is higher,and age,education level,place of residence,depressive symptoms are associated with cognitive function in CMM patients.

关 键 词：认知障碍 中年人 老年人 代谢性心血管共病 

分 类 号：R54[医药卫生—心血管疾病]