不同重建层厚和感兴趣区域厚度对定量CT骨密度值测量的影响研究  

Effect of the thicknesses of different reconstruction layer and the ROI thicknesses on the measurement of BMD value of QCT

作　　者：刘金龙 苏丹阳 张浩然 马渊博 苗秋菊 白臻 杨晓鹏[2] Liu Jinlong;Su Danyang;Zhang Haoran;Ma Yuanbo;Miao Qiuju;Bai Zhen;Yang Xiaopeng(Department of Radiology,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Equipment,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院放射科,郑州450052 [2]郑州大学第一附属医院装备部,郑州450052

出　　处：《中国医学装备》2025年第1期19-23,共5页China Medical Equipment

基　　金：河南省医学教育研究项目(WJLX2023054)。

摘　　要：目的:评估使用不同的重建层厚和不同的感兴趣区域(ROI)厚度对定量CT(QCT)测量椎体骨密度(BMD)值结果的影响。方法:回顾性收集2021年5月至9月期间在郑州大学第一附属医院接受QCT的机会性筛查骨质疏松的100例患者。将QCT重建层厚为1和5 mm的图像分别传入QCT Pro工作站,ROI厚度分别调整至5、7和9 mm。记录不同重建层厚及不同ROI厚度下的QCT测量平均BMD值。分析不同重建层厚及不同ROI厚度的选取对QCT测量BMD值的影响。结果:ROI厚度为5 mm时,重建层厚为1和5 mm的平均BMD值分别为(117.41±45.97)和(118.77±44.84)mg/cm^(3),差异有统计学意义(t=-2.283,P<0.05)。ROI厚度为7 mm时,重建层厚为1和5 mm的平均BMD值分别为(116.38±46.06)和(119.06±44.55)mg/cm^(3),差异有统计学意义(t=-3.280,P<0.05)。ROI厚度为9 mm时,重建层厚为1和5 mm的平均BMD值分别为(116.25±45.36)和(120.12±44.10)mg/cm^(3),差异有统计学意义(t=-5.841,P<0.001)。重建层厚为1和5 mm时,5、7和9 mm ROI厚度的BMD测量值差异均无统计学意义(P>0.05)。结论:QCT重建层厚对平均BMD测量值存在影响,1 mm的重建层厚更加适用于临床,而ROI厚度对QCT平均BMD测量值无显著影响。临床中可根据实际情况适当调整ROI厚度来规避骨折或椎体植入物等因素带来的影响。Objective:To assess the effect of using different thicknesses of reconstruction layer and different thicknesses of region of interest(ROI)on the results of vertebral bone mineral density(BMD)values that were measured by quantitative computed tomography(QCT).Methods:A total of 100 patients who underwent QCT screening for opportunistic osteoporosis between May and September 2021 at the First Affiliated Hospital of Zhengzhou University were retrospectively collected.Images that the thicknesses of QCT reconstruction layer were respectively 1 and 5 mm were transferred to the QCT Pro workstation,and ROI thicknesses were adjusted to 5,7,and 9 mm,respectively.The average BMD values of QCT measurements were recorded under different thicknesses of reconstruction layer and different ROI thicknesses.Then,the effects of the choose of different thicknesses of reconstruction layer and the different ROI thicknesses on BMD values that were measured by QCT were analyzed.Results:The average BMD values of 1 mm and 5 mm thicknesses of reconstruction layer were respectively(117.41±45.97)mg/cm^(3) and(118.77±44.84)mg/cm^(3) when ROI thickness was 5 mm,with a statistically significant difference(t=-2.283,P<0.05).The average BMD values of 1 mm and 5 mm thicknesses of reconstruction layer were respectively(116.38±46.06)mg/cm^(3) and(119.06±44.55)mg/cm^(3) when the ROI thickness was 7mm,and the difference was statistically significant(t=-3.280,P<0.05).The average BMD values of 1 mm and 5 mm thicknesses of reconstruction layer were respectively(116.25±45.36)mg/cm^(3) and(120.12±44.10)mg/cm^(3) when the ROI thickness was 9 mm,and the difference was statistically significant(t=-5.841,P<0.001).The differences in BMD measurement values among 5,7 and 9 mm ROI thicknesses were not statistically significant when the thicknesses of reconstruction layer were respectively 1 and 5 mm.Conclusion:There is an effect of the thickness of QCT reconstruction layer on average BMD measurement values,and 1 mm thickness of reconstruction layer is more suit

关 键 词：定量CT(QCT) 骨密度(BMD) 重建层厚 感兴趣区域(ROI) 

分 类 号：R814.42[医药卫生—影像医学与核医学]