CLEC16A基因与1型糖尿病易感相关性的研究进展  

Reviews about The Correlation between the CLEC16A Gene and Genetic Susceptibility to Type 1 Diabetes

作　　者：高恒坤 文兴贵 于维[1] GAO Hengkun;WEN Xinggui;YU Wei(China-Japan Union Hospital of Jilin University,Changchun 130033,China)

机构地区：[1]吉林大学中日联谊医院创面修复科-整形重建显微外科,吉林长春130033

出　　处：《中国实验诊断学》2025年第1期121-124,F0003,共5页Chinese Journal of Laboratory Diagnosis

基　　金：吉林省卫生人才专项(2023SCZ77,2022SCZ11)。

摘　　要：1型糖尿病的发病机制尚没有明确解释,但是遗传因素导致的自身免疫反应是得到肯定的。大量关于基因与疾病易感相关性的研究证实CLEC16A基因的多态性位点与多种疾病具有显著相关性。本文将对已证实的与1型糖尿病易感相关的CLEC16A基因多态性位点作一综述,为探究1型糖尿病发病机制和治疗提供新的思路。The pathogenesis of type 1diabetes remains unknown,but it is recognized that the autoimmune caused by genetic variation plays an important role.A lot of study on the correlation between genes and genetic susceptibility of diseases have confirmed that SNPs of CLEC16Aconfer significant susceptibility to many diseases.This article will summarise the SNPs of CLEC16Aassociated with the susceptibility to type 1diabetes.

关 键 词：CLEC16A基因 1型糖尿病 基因多态性位点 

分 类 号：R58[医药卫生—内分泌]