肠癌高凝状态的中医证型分布规律及相关性  

Distribution Pattern and Relevance of Chinese Medicine Syndrome Types ofHypercoagulable State in Colorectal Cancer

作　　者：唐宇莹 高宏[2] Tang Yuying;Gao Hong(Graduate School,Liaoning University of Traditional Chinese Medicine,Shenyang 110000,China;Department of Cancer,The Hospital Affiliated to Liaoning University of Traditional Chinese Medicine,Shenyang 110000,China)

机构地区：[1]辽宁中医药大学研究生学院,辽宁沈阳110000 [2]辽宁中医药大学附属医院肿瘤科,辽宁沈阳110000

出　　处：《亚太传统医药》2025年第2期35-39,共5页Asia-Pacific Traditional Medicine

摘　　要：目的:探讨结直肠癌血液高凝状态中医证型分布规律,以及凝血各项指标与中医证型、手术、化疗、内分泌治疗、靶向治疗等有无相关性。方法:对辽宁中医药大学附属医院肿瘤科2022-2024年结直肠恶性肿瘤血液高凝患者进行回顾性分析,分析其中医证型分布特点,并分析年龄、中医证型、手术、化疗及内分泌治疗等因素与凝血指标的关系。结果:在是否行手术治疗的患者中,PT两组之间P=0.002<0.05,差异有统计学意义。在是否行化疗治疗的患者中,APTT两组之间P=0.044<0.05,差异有统计学意义。结论:在血液高凝状态患者中,既往行手术治疗对PT存在一定的影响性;既往进行过化疗对APTT存在影响。而FIB与结直肠癌各证候之间存在着一定的相关性。这反映了血液高凝状态与不同中医病机在客观指标上的差异。Objective:To investigate the distribution of traditional Chinese medicine syndromes of blood hypercoagulability in colorectal cancer,and whether there is any correlation between blood coagulability and traditional Chinese medicine syndromes,surgeries,chemotherapy.Methods:Retrospective analysis was conducted on the patients with hypercoagulability of colorectal malignancies in the Oncology Department of Hospital Affiliated to Liaoning University of Traditional Chinese Medicine from 2022 to 2024,and the distribution characteristics of TCM syndrome types were analyzed,and the relationship between age,TCM syndrome types,surgeries,chemotherapy and endocrine therapy and coagulation indexes was analyzed.Results:There was statistical significance in PT between the two groups in patients who underwent surgery or not,P=0.002<0.05.APTT between the two groups was P=0.044<0.05,showing statistical significance in patients who received chemotherapy or not.Conclusion:In patients with hypercoagulable blood,PT may be affected by prior surgical treatment.Previous chemotherapy affected APTT.There was a certain correlation between FIB and each syndrome of colorectal cancer.This reflects the differences in objective indexes between the hypercoagulable state of blood and the pathogenesis of different TCM diseases.

关 键 词：结直肠癌 高凝状态 中医证型 相关性 

分 类 号：R273[医药卫生—中西医结合]