Hybrid coatings on dental and orthopedic titanium implants:Current advances and challenges  

作　　者：Weilong Tang Nicholas G.Fischer Xinzi Kong Ting Sang Zhou Ye 

机构地区：[1]Applied Oral Sciences and Community Dental Care,Faculty of Dentistry,The University of Hong Kong,Hong Kong,China [2]MDRCBB,Minnesota Dental Research Center for Biomaterials and Biomechanics,University of Minnesota,Minneapolis,USA [3]School of Stomatology,Jiangxi Medical College,Nanchang University,Nanchang,China [4]Key Laboratory of Oral Biomedicine&Jiangxi Province Clinical Research Center for Oral Diseases,Nanchang,China

出　　处：《BMEMat(BioMedical Engineering Materials)》2024年第4期68-94,共27页生物医学工程材料(英文)

基　　金：This study was supported by the IADR Innovation in Oral Care Awards to Z.Y.,the National Natural Science Foundation of China[grant number 82160190 to T.S.];the Jiangxi Provincial Department of Science and Technology,China[grant number 20203BBGL73156 to T.S.].

摘　　要：Dental and orthopedic titanium implants are successfully and widely used but still face challenges due to complications leading to high treatment cost,morbidity,and even mortality.This review focuses on the hybrid coatings designed to prevent and mitigate implant failure by integrating multiple strategies and materials.The forms of manufacturing and synthesizing hybrid coatings were first discussed.We then categorize these coatings based on their biological functions:antibacterial coatings,which are essential for preventing difficult-to-treat infection;coatings designed to promote osseointegration,crucial for the mechanical stability of implants;coatings that encourage soft tissue attachment,contributing to the overall success and esthetics of implant.We summarize the state of the art in multifunctional coatings that integrate multiple biological functions as an alternative,holistic approach for reducing implant complications.The review culminates in a discussion on future di-rections in the field,emphasizing the potential and notable challenges these biofunctional hybrid coatings face toward obtaining commercial success in patients.Together,our article provides a comprehensive overview of current developments and a glimpse into the future of hybrid coatings for potentially revolutionizing dental and orthopedic implants.

关 键 词：ANTIMICROBIAL implant infection multifunctional coatings OSSEOINTEGRATION soft tissue attachment 

分 类 号：TG1[金属学及工艺—金属学]