Application of cardiac magnetic resonance T1 and T2 mapping techniques in the diagnosis of acute myocarditis and the predictive value for major adverse cardiovascular events  

作　　者：LIU Jiao 

机构地区：[1]Radiographic Imaging Center,The First Affiliated Hospital,Hengyang Medical School,University of South China,Hengyang,421000,China

出　　处：《South China Journal of Cardiology》2024年第4期216-224,共9页岭南心血管病杂志(英文版)

摘　　要：Background Acute myocarditis is a disease characterized by inflammation of the heart muscle, usually caused by viral infection, autoimmune reactions, or toxins, resulting in damage and dysfunction of cardiomyocytes. In recent years, the incidence of acute myocarditis has gradually increased, especially in young people and athletes, which can cause serious cardiac complications and even lead to heart failure, cardiac arrest or major adverse cardiovascular events(MACEs). Methods A total of 90 patients with acute myocarditis(acute myocarditis group) and 30 healthy subjects(control group) admitted to our hospital from November 2021 to November 2023 were selected. Cardiac magnetic resonance(CMR) T1 and T2 mapping sequence scanning and cardiac function parameter measurement was performed on all subjects. The acute myocarditis group was followed up for 12 months and divided into the MACEs group and the non-MACEs group according to whether MACEs occurred. The differences in CMR parameters were analyzed, and receiver operating characteristic(ROC) curve was applied to analyze the predictive value of cardiac CMR T1 and T2 techniques for the occurrence of MACEs in patients with acute myocarditis. Results Compared with the control group, the level of left ventricular ejection fraction(LVEF) in the acute myocarditis group was significantly decreased, while left ventricular end-diastole volume(LVEDV), left ventricular endsystolic volume(LVESV), lactate dehydrogenase(LDH) and creatine kinase MB isoenzyme(CK-MB) increased significantly(P<0.05);T1 and T2 values, late gadolinium enhancement(LGE) percentage of left ventricle, left ventricular entropy and extracellular volume(ECV) in acute myocarditis group were significantly higher than those in the control group(P<0.05). Pearson correlation analysis showed that T1 and T2 values were negatively correlated with LVEF, while T1 and T2 values were positively correlated with LVESV, CK-MB, left ventricular entropy and ECV in patients with acute myocarditis(P<0.05). Among patients with acu

关 键 词：Cardiac magnetic resonance Mapping technology Acute myocarditis MACEs Predictive value 

分 类 号：R54[医药卫生—心血管疾病]